Evidence map›Paper›PMID 32773870›Full record

ArticleIndian journal of psychiatry

Artificial intelligence-based classification of schizophrenia: A high density electroencephalographic and support vector machine study.

Sai Krishna Tikka, Bikesh Kumar Singh, S Haque Nizamie, Shobit Garg, Sunandan Mandal, Kavita Thakur, Lokesh Kumar Singh

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Assisting schizophrenia diagnosis using clinical electroencephalography and interpretable graph neural networks: a real-world and cross-site study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Artificial intelligence and Psychiatry: An overview.Asian journal of psychiatry · 2022
    Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sai Krishna TikkaDepartment of Psychiatry, All India Institute of Medical Sciences , Raipur, Chhattisgarh, India.
Bikesh Kumar SinghDepartment of Bio-Medical Engineering, National Institute of Technology , Raipur, Chhattisgarh, India.
S Haque NizamieDepartment of Psychiatry, Central Institute of Psychiatry, Ranchi, Jharkhand, India.
Shobit GargDepartment of Psychiatry, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India.
Sunandan MandalSchool of Studies in Electronics and Photonics, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India.
Kavita ThakurSchool of Studies in Electronics and Photonics, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India.
Lokesh Kumar SinghDepartment of Psychiatry, All India Institute of Medical Sciences , Raipur, Chhattisgarh, India.
All India Institute of Medical Sciences Raipur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInterview-based schizophrenia (SCZ) diagnostic methods are not completely valid. Moreover, SCZ-the disease entity is very heterogeneous. Supervised-Machine-Learning (sML) application of Artificial-Intelligence holds a tremendous promise in solving these issues.

aimsTo sML-based discriminating validity of resting-state electroencephalographic (EEG) quantitative features in classifying SCZ from healthy and, positive (PS) and negative symptom (NS) subgroups, using a high-density recording. SETTINGS AND

designData collected at a tertiary care mental-health institute using a cross-sectional study design and analyzed at a premier Engineering Institute. MATERIALS AND

methodsData of 38-SCZ patients and 20-healthy controls were retrieved. The positive-negative subgroup classification was done using Positive and Negative Syndrome Scale operational-criteria. EEG was recorded using 256-channel high-density equipment. Eight STATISTICAL ANALYSIS: Mann-Whitney test was used for comparison of machine learning-features. Accuracy, sensitivity, specificity, and area under receiver operating characteristics-curve were measured as discriminatory indices of classifications.

resultsAccuracy of classifying SCZ from healthy and PS from NS SCZ, were 78.95% and 89.29%, respectively. While beta and gamma frequency related features most accurately classified SCZ from healthy controls, delta and theta frequency related features most accurately classified positive from negative SCZ. Inferior frontal gyrus features most accurately contributed to both the classificatory instances.

conclusionsSVM-based classification and sub-classification of SCZ using EEG data is optimal and might help in improving the "validity" and reducing the "heterogeneity" in the diagnosis of SCZ. These results might only be generalized to acute and moderately ill male SCZ patients.

Indexed as

Feature-extractionmachine-learningnegative symptomspositive symptomsvalidity

Identifiers

PMID32773870
PMCPMC7368447
OpenAlexW3024248489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.