Evidence map›Paper›PMID 32773809›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2020

[Maternal periconceptional folic acid supplementation and its effects on the prevalence of fetal neural tube defects].

L Jin, C Wang, J Zhang, W Y Meng, J Y Zhang, J H Yu, G Y Lin, M K Tong, L Jin

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

L JinDepartment of Maternal Health Care, Tongzhou Maternal and Child Health Hospital of Beijing, Beijing 101100, China.
C WangInstitute of Reproductive and Child Health, Peking University; Key Laboratory of Reproductive Health, the National Health Commission of the People's Republic of China; Department of Epidemiology and Biostatistics, Peking University School of Public Health; Beijing 100191, China.
J ZhangInstitute of Reproductive and Child Health, Peking University; Key Laboratory of Reproductive Health, the National Health Commission of the People's Republic of China; Department of Epidemiology and Biostatistics, Peking University School of Public Health; Beijing 100191, China.
W Y MengDepartment of Obstetrics, Tongzhou Maternal and Child Health Hospital of Beijing, Beijing 101100, China.
J Y ZhangDepartment of Maternal Health Care, Tongzhou Maternal and Child Health Hospital of Beijing, Beijing 101100, China.
J H YuInstitute of Reproductive and Child Health, Peking University; Key Laboratory of Reproductive Health, the National Health Commission of the People's Republic of China; Department of Epidemiology and Biostatistics, Peking University School of Public Health; Beijing 100191, China.
G Y LinDepartment of Maternal Health Care, Tongzhou Maternal and Child Health Hospital of Beijing, Beijing 101100, China.
M K TongInstitute of Reproductive and Child Health, Peking University; Key Laboratory of Reproductive Health, the National Health Commission of the People's Republic of China; Department of Epidemiology and Biostatistics, Peking University School of Public Health; Beijing 100191, China.
L JinInstitute of Reproductive and Child Health, Peking University; Key Laboratory of Reproductive Health, the National Health Commission of the People's Republic of China; Department of Epidemiology and Biostatistics, Peking University School of Public Health; Beijing 100191, China.
Chongqing Maternal and Child Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo find out the status of folic acid supplementation among women, to evaluate the prevention effects on neural tube defects (NTDs), and to explore the factors impact on folic acid supplementation compliance.

methodsBased on the routine data of 92 121 women in prenatal health care and birth defect surveillance system in Tongzhou District of Beijing from 2013 to 2018, we described the prevalence of periconceptional folic acid supplementation, pre-pregnancy folic acid supplementation and regularly folic acid supplementation (compliance supplementation). Trend

resultsThe prevalence of periconceptional folic acid supplementation during the six years was 90.08% and it was increased from 2013 to 2018, but the rate of pre-pregnancy and regular supplementation was only 41.5% and declined from 2013 to 2018, especially 2013 to 2015. The prevalence of NTDs among the fetuses whose mothers took folic acid during periconceptional period was 5.5/10 000, while the prevalence for the fetuses whose mothers did not take folic acid was 19.7/10 000 (

conclusionThe rate of folic acid supplementation among women in Tongzhou District of Beijing was relatively high, but their compliance was poor. Women who did not take folic acid during periconception seriously affected the prevention effect of NTDs. We should focus on women who are younger than 25 years old, lower educated, pre-pregnancy underweight or obese, multiparas and nonlocal household registers, in order to improve the periconceptional folic acid supplementation compliance and improve the effects of NTDs prevention.

Indexed as

Dietary SupplementsNeural Tube DefectsAdultBeijingFemaleFetusFolic AcidHumansPregnancyPrevalenceFolic AcidComplianceFolic acidNeural tube defectsPericonception

Identifiers

PMID32773809
PMCPMC7433619
OpenAlexW3049334066

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.