ReviewKidney research and clinical practice2020
Development of acute kidney injury following pediatric cardiac surgery.
Review in Kidney research and clinical practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pediatric Postoperative Acute Kidney Injury After Noncardiac Surgery: A Systematic Review and Meta-Analysis.Paediatric anaesthesia · 2026Pooled it
- Machine learning models for predicting postoperative acute kidney injury in pediatric cardiac surgery: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
- Serum lactate and capillary refill time as predictors of acute kidney injury after pediatric cardiovascular surgery: a prospective cohort study.Pediatric nephrology (Berlin, Germany) · 2026Observational
- Plasma NGAL-detected kidney injury following paediatric spine surgery: role of intraoperative hypotension.BMC nephrology · 2026Article
- Modifiable risk factors in type 1 cardiorenal syndrome in children with congenital heart disease: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Iron-related protein in prediction of acute kidney injury in the pediatric population after cardiac surgery.Journal of cardiothoracic surgery · 2025Article
- Renal Replacement Therapy in Pediatric Cardiac Intensive Care: A Retrospective Analysis of Modalities, Outcomes, and Prognostic Factors.Journal of clinical medicine · 2025Article
- Impact of acute kidney injury and dysnatremia on length of stay in infants after cardiac surgery.Pediatric nephrology (Berlin, Germany) · 2025Article
- Validation of an assay for NGAL in a pediatric population.Practical laboratory medicine · 2025Article
- Cardiac surgery-associated acute kidney injury in neonatal Norwood procedure: incidence, risk factors and impact on mortality and outcomes.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Article
- Acute kidney injury in children undergoing cardiac surgery: predictive value of kidney arterial Doppler-based variables.Pediatric nephrology (Berlin, Germany) · 2024Article
- Usefulness of the N-Terminal of the Prohormone Brain Natriuretic Peptide in Predicting Acute Kidney Injury Requiring Renal Replacement Therapy in Patients Undergoing Heart Valve Surgery.Medicina (Kaunas, Lithuania) · 2023Article
- Indexed oxygen delivery during pediatric cardiopulmonary bypass is a modifiable risk factor for postoperative acute kidney injury.The journal of extra-corporeal technology · 2023Article
- Acute kidney injury after infant cardiac surgery: a comparison of pRIFLE, KDIGO, and pROCK definitions.BMC nephrology · 2023Article
- Outcomes associated with unrecognized acute kidney injury in postoperative pediatric cardiac patients.Pediatric nephrology (Berlin, Germany) · 2023Article
- Cardiopulmonary bypass in neonates and infants: advantages of high flow high hematocrit bypass strategy-clinical practice review.Translational pediatrics · 2023Review
- Use of COJournal of cardiovascular development and disease · 2023Review
- Machine Learning-Based Prediction of Acute Kidney Injury Following Pediatric Cardiac Surgery: Model Development and Validation Study.Journal of medical Internet research · 2023Article
- Acute Kidney Injury Predictors and Outcomes after Cardiac Surgery in Children with Congenital Heart Disease: An Observational Cohort Study.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) in the pediatric population is a relatively common phenomenon. Specifically, AKI has been found in increasing numbers within the pediatric population following cardiac surgery, with up to 43% of pediatric patients developing AKI post-cardiac surgery. However, recent advances have allowed for the identification of risk factors. These can be divided into preoperative, intraoperative, and postoperative factors. Although the majority of pediatric patients developing AKI after cardiac surgery completely recover, this condition is associated with worse outcomes. These include fluid overload and increased mortality and result in longer hospital and intensive care unit stays. Detecting the presence of AKI has advanced; use of relatively novel biomarkers, including neutrophil gelatinase associated lipocalin, has shown promise in detecting more subtle changes in kidney function when compared to conventional methods. While a single, superior treatment has not been elucidated yet, novel functions of medications, including fenoldopam, theophylline and aminophylline, have been shown to have better outcomes for these patients. With the recent advances in identification of risk factors, outcomes, diagnosis, and management, the medical community can further explain the complexities of AKI in the pediatric population post-cardiac surgery.
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