Evidence map›Paper›PMID 32773328›Full record

SynthesisAcademic radiology2020

Imaging Findings of SARS-CoV-2 Infection in Pediatrics: A Systematic Review of Coronavirus Disease 2019 (COVID-19) in 850 Patients.

Sanaz Katal, Sean K Johnston, Jennifer H Johnston, Ali Gholamrezanezhad

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Academic radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. SARS-CoV-2 paediatric chest X-ray findings during the Omicron variant wave.Southern African journal of infectious diseases · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. COVID-19 in Pediatrics.Rheumatic diseases clinics of North America · 2021
    Review
  13. Review
  14. Article
  15. Imaging of COVID-19: CT, MRI, and PET.Seminars in nuclear medicine · 2021
    Review
  16. A comprehensive review of imaging findings in COVID-19 - status in early 2021.European journal of nuclear medicine and molecular imaging · 2021
    Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sanaz KatalIndependent Researcher.
Sean K JohnstonAssistant Professor of Clinical Radiology, Keck School of Medicine, University of Southern California (USC), Los Angles, CA, USA.
Jennifer H JohnstonMcGovern Medical School, Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, 6431 Fannin Street, 2.130B, Houston, TX 77030, USA.
Ali GholamrezanezhadAssistant Professor of Clinical Radiology, Keck School of Medicine, University of Southern California (USC), Los Angles, CA, USA. Electronic address: ali.gholamrezanezhad@med.usc.edu.
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RATIONALE AND

objectivesChildren with COVID-19 seem to have a relatively milder disease and better prognosis; however, severe disease or death could still occur in this age group. Although the knowledge on the clinical and epidemiology of COVID-19 in pediatric patients is being accumulated rapidly, relevant comprehensive review on its radiological manifestations is still lacking. The present article reviews the radiological characteristics of COVID-19 in pediatrics, based on the previous studies. MATERIALS AND

methodsWe conducted a systematic literature search for published articles by using Medline, Scopus, Google Scholar and Embase online databases. All studies describing CT findings of COVID-19 in pediatrics (<18years) were included.

resultsA total of 39 studies with 850 pediatric patients were reviewed. 225 (26.5%) of patients had normal CT findings. Ground-glass opacities and consolidations were the most common CT abnormalities (384/625, 61.5%). Other findings were halo sign, interstitial opacities, bronchial wall thickening, and crazy-paving sign. Approximately 55% of patients had unilateral pulmonary findings. Most studies found peripheral and lower-lobe distribution to be a prominent imaging finding.

conclusionOur study showed that imaging findings in children were often milder and more focal than adults, typically as ground-glass opacities and consolidations with unilateral lower-lobe predominance, which have been regressed during the recovery time. A balance must be struck between the risk of radiation and the need for chest CT. If still necessary, low-dose CT is more appropriate in this age group. Albeit, due to the limited number of reported pediatrics with COVID-19, and the lack of consistency in CT descriptors, further work is still needed in this regard.

Indexed as

CoronavirusCoronavirus InfectionsPandemicsPediatricsPneumonia, ViralAdultBetacoronavirusChildCOVID-19HumansLungSARS-CoV-2Chest imagingChildrenCOVID-19CT-scanLungPediatricsPneumoniaRadiationSARS-CoV-2

Identifiers

PMID32773328
PMCPMC7392075
OpenAlexW3045999715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.