Evidence map›Paper›PMID 32773297›Full record

SynthesisObesity research & clinical practice

Coronavirus (SARS-CoV-2) and the risk of obesity for critically illness and ICU admitted: Meta-analysis of the epidemiological evidence.

Silvia Helena de Carvalho Sales-Peres, Lucas José de Azevedo-Silva, Rafaela Carolina Soares Bonato, Matheus de Carvalho Sales-Peres, Ana Carolina da Silvia Pinto, Joel Ferreira Santiago Junior

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Obesity research & clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04799132 (Association Between Body Mass Index and High-flow Cannula Therapy Success in Patients With Severe Covid 19 Related Pneumonia. Retrospective Study.), which is not on this map. Cited by 36 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 8 pooled it
1.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04799132 completednot on this map

Association Between Body Mass Index and High-flow Cannula Therapy Success in Patients With Severe Covid 19 Related Pneumonia. Retrospective Study.

TypeobservationalSponsorClínica del countryRan2020 to 2021Enrolled303ConditionsCovid19, Obesity, Overweight, Pneumonia, Viral
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 8 syntheses or guidelines pooled it, 86 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Silvia Helena de Carvalho Sales-PeresDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, Brazil. Electronic address: shcperes@usp.br.
Lucas José de Azevedo-SilvaDepartment of Prosthodontics and Periodontology, Bauru School of Dentistry, University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, Brazil.
Rafaela Carolina Soares BonatoDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, Brazil.
Matheus de Carvalho Sales-PeresDepartment of Plastic Surgery, Botucatu Medical School, Botucatu, São Paulo, Brazil.
Ana Carolina da Silvia PintoDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, Brazil.
Joel Ferreira Santiago JuniorSchool of Dentistry, Unisagrado, Bauru, São Paulo, Brazil.
Universidade de São Paulo · BRUniversidade Sagrado Coração · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the relationship between coronavirus disease 2019 (COVID-19) and obesity in critically ill patients admitted to the intensive care unit (ICU).

methodsWe systematically searched PubMed, SCOPUS, Embase, LILACS, and Web of Science for studies published up to April 27, 2020. The outcome of interest was composite poor outcome, comprising mortality and severe COVID-19. We used a standardized data extraction form to collect information from published reports of eligible studies. Heterogeneity and publication bias were assessed using I

resultsNine studies including 6577 patients were selected for evaluation. The COVID-19 patients were 59.80% male and had comorbidities such as hypertension (51.51%), diabetes (30.3%), cardiovascular disease (16.66%), lung disease (15.99%), renal disease (7.49%), cancer (5.07%), and immunosuppression (1.8%). For patients with severe complications, the overall pooled event rates were 56.2% (random; 95% CI: 35.3-75.1; p = 0.015; I DISCUSSION: This systematic review indicated the relationship between obesity, ICU admission, severe COVID-19, and disease progression in patients with COVID-19. Obese patients with hypertension, type 2 diabetes, smoking habit, lung disease, and/or cardiovascular disease should be cared for with increased attention.

Indexed as

BetacoronavirusAdultAgedComorbidityCoronavirus InfectionsCOVID-19Critical IllnessFemaleHospitalizationHumansIntensive Care UnitsMaleMiddle AgedObesityPandemicsPneumonia, ViralCOVID-19HospitalizationICUIntubationObesitySARS-CoV-2

Identifiers

PMID32773297
PMCPMC7396969
OpenAlexW3046548178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.