ArticleeLife2020
Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Developmental bias of body size and caste by the fire ant social supergene.Proceedings. Biological sciences · 2026Article
- Molecular Evolution of a Sex-Linked Inversion Polymorphism in Zebra Finches.Genome biology and evolution · 2026Article
- Functional genetic elements of a butterfly mimicry supergene.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Molecular Adjustment to a Social Niche: Brain Transcriptomes Reveal Divergent Influence of Social Environment on the Two Queen Morphs of the Ant Temnothorax rugatulus.Molecular ecology · 2025Article
- The Fire Ant Social Chromosome Exerts a Major Influence on Genome Regulation.Molecular biology and evolution · 2025Article
- An odorant-binding protein functions in fire ant social immunity interfacing with innate immunity.Open biology · 2025Article
- Social antagonism facilitates supergene expansion in ants.Current biology : CB · 2023Article
- Dynamic molecular evolution of a supergene with suppressed recombination in white-throated sparrows.eLife · 2022Article
- Radiation and hybridization underpin the spread of the fire ant social supergene.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Iterative evolution of supergene-based social polymorphism in ants.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- A socially polymorphic Formica ant species exhibits a novel distribution of social supergene genotypes.Journal of evolutionary biology · 2022Article
- Individual-based Modeling of Genome Evolution in Haplodiploid Organisms.Genome biology and evolution · 2022Article
- Recurring adaptive introgression of a supergene variant that determines social organization.Nature communications · 2022Article
- A neutral model for the loss of recombination on sex chromosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- The Genomic Architecture and Evolutionary Fates of Supergenes.Genome biology and evolution · 2021Review
- Functional genomics of supergene-controlled behavior in the white-throated sparrow.Faculty reviews · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Supergene regions maintain alleles of multiple genes in tight linkage through suppressed recombination. Despite their importance in determining complex phenotypes, our empirical understanding of early supergene evolution is limited. Here we focus on the young 'social' supergene of fire ants, a powerful system for disentangling the effects of evolutionary antagonism and suppressed recombination. We hypothesize that gene degeneration and social antagonism shaped the evolution of the fire ant supergene, resulting in distinct patterns of gene expression. We test these ideas by identifying allelic differences between supergene variants, characterizing allelic expression across populations, castes and body parts, and contrasting allelic expression biases with differences in expression between social forms. We find strong signatures of gene degeneration and gene-specific dosage compensation. On this background, a small portion of the genes has the signature of adaptive responses to evolutionary antagonism between social forms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.