ArticleeLife2020
Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Cannabidiol dose modulates behavioral response to acute and repeated administration of Δ9-Tetrahydrocannabinol by strain and sex.bioRxiv : the preprint server for biology · 2026Article
- Autophagy and Neuropsychiatric Disorders: Unraveling Molecular Mechanisms and Signaling Pathways.CNS & neurological disorders drug targets · 2026Review
- The emerging role of autophagy in the rewarding and stimulant behaviors in models of substance use disorder.Frontiers in neuroscience · 2026Review
- Cannabis as a Source of Approved Drugs: A New Look at an Old Problem.Molecules (Basel, Switzerland) · 2023Review
- The CB1 cannabinoid receptor regulates autophagy in the tibialis anterior skeletal muscle in mice.Biological research · 2023Article
- Combined alcohol and cannabinoid exposure leads to synergistic toxicity by affecting cerebellar Purkinje cells.Nature metabolism · 2022Article
- Receptor mechanisms underlying the CNS effects of cannabinoids: CBAdvances in pharmacology (San Diego, Calif.) · 2022Article
- Identification of BiP as a CBThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Review
- Cannabinoid-induced motor dysfunctionAutophagy · 2020Article
Corrections and comments
- Commented on by
Authors and funding
14 authors at 4 institutions in 2 countries.
Cristina BlázquezCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto Universitario de Investigación Neuroquímica (IUIN) and Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain.
Andrea Ruiz-CalvoCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto Universitario de Investigación Neuroquímica (IUIN) and Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain.
Raquel Bajo-GrañerasCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto Universitario de Investigación Neuroquímica (IUIN) and Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain.
Jérôme M BaufretonCentre National de la Recherche Scientifique (CNRS) and University of Bordeaux, Institut des Maladies Neurodégénératives, Bordeaux, France.ORCID 0000-0002-2623-6375
Eva ReselCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto Universitario de Investigación Neuroquímica (IUIN) and Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain.
Marjorie VarilhInstitut National de la Santé et de la Recherche Médicale (INSERM) and University of Bordeaux, NeuroCentre Magendie, Physiopathologie de la Plasticité Neuronale, Bordeaux, France.
Antonio C Pagano ZottolaInstitut National de la Santé et de la Recherche Médicale (INSERM) and University of Bordeaux, NeuroCentre Magendie, Physiopathologie de la Plasticité Neuronale, Bordeaux, France.
Yamuna MarianiInstitut National de la Santé et de la Recherche Médicale (INSERM) and University of Bordeaux, NeuroCentre Magendie, Physiopathologie de la Plasticité Neuronale, Bordeaux, France.
Astrid CannichInstitut National de la Santé et de la Recherche Médicale (INSERM) and University of Bordeaux, NeuroCentre Magendie, Physiopathologie de la Plasticité Neuronale, Bordeaux, France.
José A Rodríguez-NavarroInstituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Giovanni MarsicanoInstitut National de la Santé et de la Recherche Médicale (INSERM) and University of Bordeaux, NeuroCentre Magendie, Physiopathologie de la Plasticité Neuronale, Bordeaux, France.
Ismael Galve-RoperhCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto Universitario de Investigación Neuroquímica (IUIN) and Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain.ORCID 0000-0003-3501-2434
Luigi BellocchioInstitut National de la Santé et de la Recherche Médicale (INSERM) and University of Bordeaux, NeuroCentre Magendie, Physiopathologie de la Plasticité Neuronale, Bordeaux, France.
Manuel GuzmánCentro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto Universitario de Investigación Neuroquímica (IUIN) and Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain.ORCID 0000-0001-7475-118X
Biomedical Research Networking Center on Neurodegenerative Diseases · ESUniversité de Bordeaux · FRCentre National de la Recherche Scientifique · FRInstituto Ramón y Cajal de Investigación Sanitaria · ES
Funding
Agence Nationale de la Recherche ANR-10-LABX-0043Agence Nationale de la Recherche ANR-16-CE37-0010-01Agence Nationale de la Recherche ANR-18-CE14-0029-01Agence Nationale de la Recherche ANR 18-CE16-0001-02Agence Nationale de la Recherche ANR-19-CE14Fondation pour la Recherche Medicale DPP20151033974Fondation pour la Recherche Médicale ARF20140129235Fondation pour la Recherche Médicale DRM20101220445H2020 European Research Council ERC-2010-StG-260515H2020 European Research Council ERC-2014-PoC-640923H2020 European Research Council ERC-2018-AdG-786467Human Frontier Science Program RGP0036/2014Spanish Ministerio de Ciencia, Innovación y Universidades RTI2018-095311-B-I00Spanish Ministerio de Ciencia, Innovación y Universidades SAF2015-64945-RSpanish Ministerio de Ciencia, Innovación y Universidades SAF2016-78666-R
Abstract
The use of cannabis is rapidly expanding worldwide. Thus, innovative studies aimed to identify, understand and potentially reduce cannabis-evoked harms are warranted. Here, we found that Δ
Indexed as
AnimalsAutophagyCannabinoidsMaleMiceMice, Inbred C57BLMice, KnockoutPsychomotor PerformancePutamenSubstantia NigraCannabinoidsautophagycannabinoiddrug abusemotor behaviourmousemTORneurosciencestriatum
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.