ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2020
Evolution of animal immunity in the light of beneficial symbioses.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed.
- Review
- Is a Commensal Here, a Pathogen There? Genotype Specific Responses by the Sea Anemone Nematostella vectensis to Vibrio Species.Molecular ecology · 2026Article
- Symbiont evolutionary history underpins quality to an insect host.Journal of insect science (Online) · 2026Article
- Natural and Engineered Halloysite Clay Interact with Bacteria in a Double-Edged Manner.ACS applied bio materials · 2026Article
- Marine Heatwaves, Ocean Warming and Acidification Reshape Reef Fish Gut Microbiomes.Molecular ecology · 2026Article
- Leaffooted bugs enrich local soil with their horizontally acquired symbiont.Frontiers in microbiology · 2026Article
- Gut bacteria induce heterologous immune priming in Rhodnius prolixus encompassing both humoral and cellular immune responses.PLoS pathogens · 2025Article
- Review
- Clinical profiling of skin microbiome and metabolome during re-epithelialization.Scientific reports · 2025Article
- Stomach Microbiome Simplification of a Coral Reef Fish at Its Novel Cold-Range Edge Under Climate Change.Molecular ecology · 2025Article
- The Microbiota and Evolution of Obesity.Endocrine reviews · 2025Review
- The Chromosome-level Genome of the Ctenophore Mnemiopsis leidyi A. Agassiz, 1865 Reveals a Unique Immune Gene Repertoire.Genome biology and evolution · 2025Article
- Article
- Symbioses between fungi and bacteria: from mechanisms to impacts on biodiversity.Current opinion in microbiology · 2024Review
- Transcriptomic responses of Mediterranean sponges upon encounter with symbiont microbial consortia.BMC genomics · 2024Article
- Insect-microbe interactions and their influence on organisms and ecosystems.Ecology and evolution · 2024Review
- Gut microbiota modulation enhances the immune capacity of lizards under climate warming.Microbiome · 2024Article
- Intracellular symbiont Symbiodolus is vertically transmitted and widespread across insect orders.The ISME journal · 2024Article
- The effect of infection with the entomopathogenic fungusFrontiers in immunology · 2024Article
- The impacts of host association and perturbation on symbiont fitness.Symbiosis (Philadelphia, Pa.) · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune system processes serve as the backbone of animal defences against pathogens and thus have evolved under strong selection and coevolutionary dynamics. Most microorganisms that animals encounter, however, are not harmful, and many are actually beneficial. Selection should act on hosts to maintain these associations while preventing exploitation of within-host resources. Here, we consider how several key aspects of beneficial symbiotic associations may shape host immune system evolution. When host immunity is used to regulate symbiont populations, there should be selection to evolve and maintain targeted immune responses that recognize symbionts and suppress but not eliminate symbiont populations. Associating with protective symbionts could relax selection on the maintenance of redundant host-derived immune responses. Alternatively, symbionts could facilitate the evolution of host immune responses if symbiont-conferred protection allows for persistence of host populations that can then adapt. The trajectory of immune system evolution will likely differ based on the type of immunity involved, the symbiont transmission mode and the costs and benefits of immune system function. Overall, the expected influence of beneficial symbiosis on immunity evolution depends on how the host immune system interacts with symbionts, with some interactions leading to constraints while others possibly relax selection on immune system maintenance. This article is part of the theme issue 'The role of the microbiome in host evolution'.
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