Evidence map›Paper›PMID 32772385›Full record

ArticleMedical physics2020

DICOM re-encoding of volumetrically annotated Lung Imaging Database Consortium (LIDC) nodules.

Andrey Fedorov, Matthew Hancock, David Clunie, Mathias Brochhausen, Jonathan Bona, Justin Kirby, John Freymann, Steve Pieper, Hugo J W L Aerts, Ron Kikinis and 1 more

Abstract read
In one paragraph

Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrey FedorovBrigham and Women's Hospital, Boston, MA, 02115, USA.
Matthew HancockFlorida State University, Tallahassee, FL, 32306, USA.
David CluniePixelMed Publishing, Bangor, PA, 18013, USA.
Mathias BrochhausenUniversity of Florida Health, Gainesville, FL, 32605, USA.
Jonathan BonaUniversity of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Justin KirbyFrederick National Laboratory for Cancer Research, Frederick, MD, 21701, USA.
John FreymannFrederick National Laboratory for Cancer Research, Frederick, MD, 21701, USA.
Steve PieperIsomics Inc., Cambridge, MA, 02138, USA.
Hugo J W L AertsBrigham and Women's Hospital, Boston, MA, 02115, USA.
Ron KikinisBrigham and Women's Hospital, Boston, MA, 02115, USA.
Fred PriorUniversity of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.

Funding

TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision MedicineU24CA215109 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI BANERJEE, IMON, PRIOR, FRED WILLIAM · 2017 to 2021
$8.5M
Unraveling the Complexities of Risk and Mechanism in CancerR35CA220523 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI QUACKENBUSH, JOHN · 2018 to 2024
$6.0M
Quantitative Image Informatics for Cancer Research (QIICR)U24CA180918 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI FEDOROV, ANDRIY, KIKINIS, RON · 2013 to 2017
$4.0M
Extensible open-source zero-footprint web viewer for oncologic imaging researchU24CA199460 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, GORDON J · 2015 to 2019
$3.5M
Genotype and Imaging Phenotype Biomarkers in Lung CancerU01CA190234 · NCI · DANA-FARBER CANCER INST · PI AERTS, HUGO, QUACKENBUSH, JOHN · 2015 to 2019
$3.3M
Resources for development and validation of Radiomic analyses & Adaptive TherapyU01CA187013 · NCI · WASHINGTON UNIVERSITY · PI PRIOR, FRED WILLIAM, SHARMA, ASHISH · 2014 to 2018
$2.6M
CCR NIH HHS HHSN261200800001CFoundation for the National Institutes of HealthNational Cancer Institute: U24 CA180918, U24 CA199460 and U01 CA190234NCI NIH HHS HHSN261200800001ENCI NIH HHS R35 CA220523NCI NIH HHS U01 CA187013NCI NIH HHS U01 CA190234NCI NIH HHS U24 CA180918NCI NIH HHS U24 CA199460NCI NIH HHS U24 CA215109NIH HHS 16X011NIH HHS 19X037QNIH HHS HHSN26100071NIH HHS HHSN261200800001E,
6 · The paper itself

Abstract

purposeThe dataset contains annotations for lung nodules collected by the Lung Imaging Data Consortium and Image Database Resource Initiative (LIDC) stored as standard DICOM objects. The annotations accompany a collection of computed tomography (CT) scans for over 1000 subjects annotated by multiple expert readers, and correspond to "nodules ≥ 3 mm", defined as any lesion considered to be a nodule with greatest in-plane dimension in the range 3-30 mm regardless of presumed histology. The present dataset aims to simplify reuse of the data with the readily available tools, and is targeted towards researchers interested in the analysis of lung CT images. ACQUISITION AND VALIDATION

methodsOpen source tools were utilized to parse the project-specific XML representation of LIDC-IDRI annotations and save the result as standard DICOM objects. Validation procedures focused on establishing compliance of the resulting objects with the standard, consistency of the data between the DICOM and project-specific representation, and evaluating interoperability with the existing tools. DATA FORMAT AND USAGE NOTES: The dataset utilizes DICOM Segmentation objects for storing annotations of the lung nodules, and DICOM Structured Reporting objects for communicating qualitative evaluations (nine attributes) and quantitative measurements (three attributes) associated with the nodules. The total of 875 subjects contain 6859 nodule annotations. Clustering of the neighboring annotations resulted in 2651 distinct nodules. The data are available in TCIA at https://doi.org/10.7937/TCIA.2018.h7umfurq. POTENTIAL APPLICATIONS: The standardized dataset maintains the content of the original contribution of the LIDC-IDRI consortium, and should be helpful in developing automated tools for characterization of lung lesions and image phenotyping. In addition to those properties, the representation of the present dataset makes it more FAIR (Findable, Accessible, Interoperable, Reusable) for the research community, and enables its integration with other standardized data collections.

Indexed as

Lung NeoplasmsDatabases, FactualHumansLungTomography, X-Ray Computedcancer imagingDICOMFAIR dataimage annotationslung cancerquantitative imaging

Identifiers

PMID32772385
PMCPMC7721965

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.