Evidence map›Paper›PMID 32772230›Full record

ReviewHuman cell2020

LncRNA DDX11-AS1: a novel oncogene in human cancer.

Yubin Feng, Maomao Wu, Shuang Hu, Xiaoqing Peng, Feihu Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Human cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Article
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  6. Review
  7. Review
  8. Article
  9. LncRNAs in modulating cancer cell resistance to paclitaxel (PTX) therapy.Medical oncology (Northwood, London, England) · 2024
    Review
  10. Review
  11. Article
  12. Article
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  16. Knockdown ofAnnals of translational medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yubin Feng *Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, 230032, Anhui Province, China.
Maomao Wu *Department of Pharmacy, Anhui Chest Hospital, Hefei, Anhui Province, China.
Shuang HuInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, 230032, Anhui Province, China.
Xiaoqing PengInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, 230032, Anhui Province, China. pengxiaoqing@ahmu.edu.cn.
Feihu ChenInflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, 230032, Anhui Province, China. chenfeihu@ahmu.edu.cn.

Funding

Anhui Science and Technology Major Project 17030801020Chen Feihu Central Support for Local-Provincial Translational Medicine Project in 2017 2017zhyx31
6 · The paper itself

Abstract

Long noncoding RNA (lncRNA) is a newly identified type of noncoding RNA with a length of more than 200 nucleotides. The latest research shows that lncRNAs play important roles in the occurrence and development of human tumours by acting both as carcinogenic genes and as tumour suppressor genes. LncRNAs plays a role in various biological processes, such as cell growth, apoptosis, migration and invasion. The newly discovered lncRNA DDX11-AS1 is abnormally highly expressed in various malignant tumours, such as hepatocellular carcinoma, colorectal cancer, osteosarcoma, bladder cancer, NSCLC and gastric cancer. DDX11-AS1 mainly regulates the expression of related genes through direct or indirect ways to perform its functions in carcinogenicity. These results indicate that DDX11-AS1 may be a marker or therapeutic target of tumours. This review summarizes the biological function and mechanism of DDX11-AS1 in the process of tumour development.

Indexed as

ApoptosisBiomarkers, TumorCarcinogenesisCell ProliferationDEAD-box RNA HelicasesDNA HelicasesGene Expression Regulation, NeoplasticGenes, Tumor SuppressorHumansMolecular Targeted TherapyNeoplasm InvasivenessNeoplasmsOncogenesPrognosisRNA, Long NoncodingBiomarkers, TumorDDX11 protein, humanDEAD-box RNA HelicasesDNA HelicasesRNA, Long NoncodingDiagnosislncRNA DDX11-ASAPrognosisTherapeutic target

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.