Evidence map›Paper›PMID 32772125›Full record

ArticleArchives of microbiology2021

Antibiofilm activities of the cinnamon extract against Vibrio parahaemolyticus and Escherichia coli.

Chengrong Lu, Huan Liu, Wendan Shangguan, Song Chen, Qingping Zhong

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 45 citations in OpenAlex.

  1. Aqueous extracts ofBiofilm · 2025
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  3. Effect ofBiology · 2024
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  6. Effect ofFrontiers in cellular and infection microbiology · 2024
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  7. Article
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  9. Antimicrobial Efficacy of Cinnamon Essential Oil against Avian PathogenicAnimals : an open access journal from MDPI · 2023
    Article
  10. Review
  11. Article
  12. Molecules (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
  15. Antibiofilm and Antiquorum Sensing Potential ofFoods (Basel, Switzerland) · 2022
    Article
  16. CRISPRiFrontiers in nutrition · 2022
    Article
  17. Frontiers in cellular and infection microbiology · 2022
    Review
  18. Article
  19. Article
  20. The exploration of anti-Frontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chengrong LuSCAU (Chaozhou) Food Institute Co. Ltd., Chaozhou, 521000, China.
Huan LiuSCAU (Chaozhou) Food Institute Co. Ltd., Chaozhou, 521000, China.
Wendan ShangguanSCAU (Chaozhou) Food Institute Co. Ltd., Chaozhou, 521000, China.
Song ChenSCAU (Chaozhou) Food Institute Co. Ltd., Chaozhou, 521000, China.
Qingping ZhongSCAU (Chaozhou) Food Institute Co. Ltd., Chaozhou, 521000, China. zhongqp@scau.edu.cn.ORCID http://orcid.org/0000-0003-0496-9153
South China Agricultural University · CN

Funding

National Key R&D Program of China 2017YFC1601203National Natural Science Foundation of China 31972046"Sailing Plan" Innovation and Entrepreneurship Team Project of Guangdong Province, China 2016YT03S056
6 · The paper itself

Abstract

Vibrio parahaemolyticus and Escherichia coli are two major foodborne pathogens. In this paper, the antibiofilm activities of the ethanol extract of cinnamon against these two bacteria were studied in detail. The antibacterial activity and the MIC of the extract were determined, and the inhibition and removing effects of the extract on the biofilms of V. parahaemolyticus and E. coli were investigated. The biofilms stained with fluorescein isothiocyanate (FITC) and concanavalin A (Con A) were also observed by confocal laser scanning microscope (CLSM). The results indicated that the extract exhibited high antibacterial activity, with the MIC against V. parahaemolyticus and E. coli was 6.25 mg/mL. The effects on V. parahaemolyticus biofilm were significant with the inhibition rate of 75.46% at MIC, and the eradication rate of 93.26% at 32MIC, respectively. As to E. coli, the inhibition rate was 48.18% at MIC, and the eradication rate was 46.16% at 8MIC. Meanwhile, the extract could notably reduce the metabolic activities and the secretion of EPS in biofilm, it inhibited 78.57% EPS formation in V. parahaemolyticus biofilm at MIC, and eliminated 61.28% EPS in mature biofilm at 4MIC. CLSM images showed that the EPS of the treated biofilm became thinner and biofilm structure was looser, when compared with the untreated control. This study elucidated that the cinnamon extract was effective to prevent biofilm formation and eradicate mature biofilms of V. parahaemolyticus and E. coli.

Indexed as

Anti-Bacterial AgentsBiofilmsCinnamomum zeylanicumEscherichia coliMicrobial Sensitivity TestsMicroscopy, ConfocalPlant ExtractsVibrio parahaemolyticusAnti-Bacterial AgentsPlant ExtractsAntibiofilmCinnamon extractEscherichia coliVibrio parahaemolyticus

Identifiers

PMID32772125
OpenAlexW3048196795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.