Evidence map›Paper›PMID 32771560›Full record

ArticleThe Journal of allergy and clinical immunology2020

Asthma among hospitalized patients with COVID-19 and related outcomes.

Stephanie Lovinsky-Desir, Deepti R Deshpande, Aliva De, Laurie Murray, Jeanette A Stingone, Angela Chan, Neha Patel, Nooralam Rai, Emily DiMango, Joshua Milner and 1 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05220488 (Fear of COVID-19 and Physical Activity Level of Children With Asthma), which is not on this map. Cited by 78 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 12 pooled it
3.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05220488 completednot on this mapstarted 2022, after this paper: background citation

Fear of COVID-19 and Physical Activity Level of Children With Asthma

TypeobservationalSponsorBartın UnıversityRan2022 to 2022Enrolled80ConditionsAsthma in ChildrenArmsAssessment
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 12 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. Pooled it
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  3. Asthma and risk of infection, hospitalization, ICU admission and mortality from COVID-19: Systematic review and meta-analysis.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Pooled it
  4. The impact of comorbid allergic airway disease on the severity and mortality of COVID-19: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Pooled it
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  10. Asthma in patients with coronavirus disease 2019: A systematic review and meta-analysis.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021
    Pooled it
  11. Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and Meta-Analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Pooled it
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Stephanie Lovinsky-DesirDivision of Pediatric Pulmonology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY. Electronic address: sl3230@cumc.columbia.edu.
Deepti R DeshpandeDivision of Allergy, Immunology and Rheumatology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY.
Aliva DeDivision of Pediatric Pulmonology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY.
Laurie MurrayDepartment of Pediatrics, New York Presbyterian - Morgan Stanley Children's Hospital of New York, New York, NY.
Jeanette A StingoneDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY.
Angela ChanDivision of Allergy, Immunology and Rheumatology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY.
Neha PatelDivision of Pediatric Pulmonology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY.
Nooralam RaiDivision of Pediatric Pulmonology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY.
Emily DiMangoDivision of Pulmonary, Allergy and Critical Care Medicine, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY.
Joshua MilnerDivision of Allergy, Immunology and Rheumatology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY.
Meyer KattanDivision of Pediatric Pulmonology, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, New York, NY.
Columbia University · USColumbia University Irving Medical Center · USMorgan Stanley Children's Hospital · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
ANESTHESIOLOGY RESEARCH TRAININGT32GM008464 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI CHARLES W EMALA, May Hua · 1992 to 2026
$6.0M
Physical Activity and Dose of Air Pollution in Pediatric Urban Asthma: Impact of Minute VentilationK01HL140216 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOVINSKY-DESIR, STEPHANIE · 2018 to 2021
$692k
NCATS NIH HHS L40 TR003188NHLBI NIH HHS K01 HL140216NIEHS NIH HHS P30 ES009089NIGMS NIH HHS T32 GM008464
6 · The paper itself

Abstract

backgroundSeveral underlying conditions have been associated with severe acute respiratory syndrome coronavirus 2 illness, but it remains unclear whether underlying asthma is associated with worse coronavirus disease 2019 (COVID-19) outcomes.

objectiveGiven the high prevalence of asthma in the New York City area, our objective was to determine whether underlying asthma was associated with poor outcomes among hospitalized patients with severe COVID-19 compared with patients without asthma.

methodsElectronic heath records were reviewed for 1298 sequential patients 65 years or younger without chronic obstructive pulmonary disease who were admitted to our hospital system with a confirmed positive severe acute respiratory syndrome coronavirus 2 test result.

resultsThe overall prevalence of asthma among all hospitalized patients with COVID-19 was 12.6%, yet a higher prevalence (23.6%) was observed in the subset of 55 patients younger than 21 years. There was no significant difference in hospital length of stay, need for intubation, length of intubation, tracheostomy tube placement, hospital readmission, or mortality between patients with and without asthma. Observations between patients with and without asthma were similar when stratified by obesity, other comorbid conditions (ie, hypertension, hyperlipidemia, and diabetes), use of controller asthma medication, and absolute eosinophil count.

conclusionsAmong hospitalized patients 65 years or younger with severe COVID-19, asthma diagnosis was not associated with worse outcomes, regardless of age, obesity, or other high-risk comorbidities. Future population-based studies are needed to investigate the risk of developing COVID-19 among patients with asthma once universal testing becomes readily available.

Indexed as

AdultAsthmaBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansLength of StayMaleMiddle AgedNew York CityPandemicsPatient ReadmissionPneumonia, ViralPrevalenceSARS-CoV-2coronavirusNew York Cityrespiratory diseaseSARS-CoV-2

Identifiers

PMID32771560
PMCPMC7409831
OpenAlexW3047265874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.