Evidence map›Paper›PMID 32771016›Full record

ArticleParticle and fibre toxicology2020

Particle characterization and toxicity in C57BL/6 mice following instillation of five different diesel exhaust particles designed to differ in physicochemical properties.

Katja Maria Bendtsen, Louise Gren, Vilhelm Berg Malmborg, Pravesh Chandra Shukla, Martin Tunér, Yona J Essig, Annette M Krais, Per Axel Clausen, Trine Berthing, Katrin Loeschner and 4 more

Open access · goldAbstract read
In one paragraph

Article in Particle and fibre toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 85 citations in OpenAlex.

  1. Trial
  2. Real-time record of particulate matter along traffic roads and health risk assessment.Environmental science and pollution research international · 2026
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  20. Importance of Punctual Monitoring to Evaluate the Health Effects of Airborne Particulate Matter.International journal of environmental research and public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Katja Maria BendtsenNational Research Centre for the Working Environment, Lersø Parkallé 105, DK-2100, Copenhagen, Denmark.
Louise GrenDivision of Ergonomics and Aerosol Technology, Lund University, Box 117, 221 00, Lund, Sweden.
Vilhelm Berg MalmborgDivision of Ergonomics and Aerosol Technology, Lund University, Box 117, 221 00, Lund, Sweden.
Pravesh Chandra ShuklaDivision of Combustion Engines, Lund University, Box 117, 221 00, Lund, Sweden.
Martin TunérDivision of Combustion Engines, Lund University, Box 117, 221 00, Lund, Sweden.
Yona J EssigDepartment for Occupational and Environmental Medicine, Institute of Laboratory Medicine, Lund University, 221 00, Lund, Sweden.
Annette M KraisDepartment for Occupational and Environmental Medicine, Institute of Laboratory Medicine, Lund University, 221 00, Lund, Sweden.
Per Axel ClausenNational Research Centre for the Working Environment, Lersø Parkallé 105, DK-2100, Copenhagen, Denmark.
Trine BerthingNational Research Centre for the Working Environment, Lersø Parkallé 105, DK-2100, Copenhagen, Denmark.
Katrin LoeschnerResearch Group for Nano-Bio Science, National Food Institute,Technical University of Denmark, Kemitorvet, Building 201, DK-2800, Kgs. Lyngby, Denmark.
Nicklas Raun JacobsenNational Research Centre for the Working Environment, Lersø Parkallé 105, DK-2100, Copenhagen, Denmark.
Henrik WolffFinnish Institute of Occupational Health, Työterveyslaitos, P.O. Box 40, FI-00032, Helsinki, Finland.
Joakim PagelsDivision of Ergonomics and Aerosol Technology, Lund University, Box 117, 221 00, Lund, Sweden.
Ulla Birgitte VogelNational Research Centre for the Working Environment, Lersø Parkallé 105, DK-2100, Copenhagen, Denmark. ubv@nfa.dk.ORCID 0000-0001-6807-1524
Lund University · SENational Research Centre for the Working Environment · DKFinnish Institute of Occupational Health · FITechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiesel exhaust is carcinogenic and exposure to diesel particles cause health effects. We investigated the toxicity of diesel exhaust particles designed to have varying physicochemical properties in order to attribute health effects to specific particle characteristics. Particles from three fuel types were compared at 13% engine intake O

resultsModerate variations were seen in physical properties for the five particles: primary particle diameter: 15-22 nm, specific surface area: 152-222 m

conclusionsWe studied diesel exhaust particles designed to differ in physicochemical properties. Our study highlights specific surface area, elemental carbon content, PAHs and ROS-generating potential as physicochemical predictors of diesel particle toxicity.

Indexed as

AnimalsCarbonCarcinogensDNA DamageGasolineLungMiceMice, Inbred C57BLParticulate MatterPolycyclic Aromatic HydrocarbonsVehicle EmissionsCarbonCarcinogensGasolineParticulate MatterPolycyclic Aromatic HydrocarbonsVehicle EmissionsDiesel exhaust particles - ultrafine particlesExhaust gas recirculationIntratracheal instillationRenewable diesel fuelsToxicity

Identifiers

PMID32771016
PMCPMC7414762
OpenAlexW3047826264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.