ArticleHealth research policy and systems2020
The opioid crisis: need for systems science research.
Article in Health research policy and systems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Psychosocial factors associated with overdose subsequent to Illicit Drug use: a systematic review and narrative synthesis.Harm reduction journal · 2024Pooled it
- A Systematic Review of Simulation Models to Track and Address the Opioid Crisis.Epidemiologic reviews · 2022Pooled it
- Economic Evaluation in Opioid Modeling: Systematic Review.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2021Pooled it
- Evaluating the Impact of Drug Regulation Stringency on Global Drug-Use Patterns: A Cross-Sectional Study.AJPM focus · 2026Article
- Social and behavioral correlates of sleep health among adults receiving medication treatment for opioid use disorder.Addiction research & theory · 2025Article
- Predicting fatal opioid-involved overdoses: A social-ecological framework matched to a linked-data warehouse.The International journal on drug policy · 2025Article
- Relative importance of socioecological domains to predicting opioid-involved mortality.PloS one · 2025Article
- A Dynamic Model of Opioid Overdose Deaths in Canada during the Co-Occurring Opioid Overdose Crisis and COVID-19 Pandemic.International journal of environmental research and public health · 2024Article
- Opioid-related harms and care impacts of conventional and AI-based prescription management strategies: insights from leveraging agent-based modeling and machine learning.Frontiers in digital health · 2023Article
- Reducing opioid use disorder and overdose deaths in the United States: A dynamic modeling analysis.Science advances · 2022Article
- Modeling the evolution of the US opioid crisis for national policy development.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Using community engagement to implement evidence-based practices for opioid use disorder: A data-driven paradigm & systems science approach.Drug and alcohol dependence · 2021Article
- Data Needs in Opioid Systems Modeling: Challenges and Future Directions.American journal of preventive medicine · 2021Article
- Dynamics of Parental Opioid Use and Children's Health and Well-Being: An Integrative Systems Mapping Approach.Frontiers in psychology · 2021Article
- Long-Term Effects of Increasing Buprenorphine Treatment Seeking, Duration, and Capacity on Opioid Overdose Fatalities: A Model-based Analysis.Journal of addiction medicineArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The opioid epidemic in the United States has had a devastating impact on millions of people as well as on their families and communities. The increased prevalence of opioid misuse, use disorder and overdose in recent years has highlighted the need for improved public health approaches for reducing the tremendous harms of this illness. In this paper, we explain and call for the need for more systems science approaches, which can uncover the complexities of the opioid crisis, and help evaluate, analyse and forecast the effectiveness of ongoing and new policy interventions. Similar to how a stream of systems science research helped policy development in infectious diseases and obesity, more systems science research is needed in opioids.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.