Evidence map›Paper›PMID 32770779›Full record

ArticleMagnetic resonance in medicine2021

Comparison of single breath hyperpolarized

Andrew McCallister, Sang Hun Chung, Michael Antonacci, Margret Z Powell, Agathe S Ceppe, Scott H Donaldson, Yueh Z Lee, Rosa Tamara Branca, Jennifer L Goralski

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03482960 (Comparison of 129Xe MRI With 19F MRI in CF Lung Disease), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03482960 early_phase1completednot on this map

Comparison of 129Xe MRI With 19F MRI in CF Lung Disease

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2018 to 2019Enrolled11ConditionsCystic FibrosisArmsHyperpolarized Xenon gas, PFP
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Pulmonary MRI in Newborns and Children.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  3. Article
  4. DynamicJHLT open · 2025
    Article
  5. Observational
  6. Reproducible Research Practices in Magnetic Resonance Neuroimaging: A Review Informed by Advanced Language Models.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  7. Article
  8. Feasibility of free-breathingMagnetic resonance in medicine · 2023
    Article
  9. Article
  10. Review
  11. Comparison of single breath hyperpolarizedMagnetic resonance in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Andrew McCallisterDepartment of Physics and Astronomy, The University of North Carolina, Chapel Hill, NC, USA.
Sang Hun ChungDepartment of Biomedical Engineering, The University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0002-0605-9420
Michael AntonacciDepartment of Physics and Astronomy, The University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0001-9363-3234
Margret Z PowellMarsico Lung Institute/UNC Cystic Fibrosis Center, The University of North Carolina, Chapel Hill, NC, USA.
Agathe S CeppeMarsico Lung Institute/UNC Cystic Fibrosis Center, The University of North Carolina, Chapel Hill, NC, USA.
Scott H DonaldsonMarsico Lung Institute/UNC Cystic Fibrosis Center, The University of North Carolina, Chapel Hill, NC, USA.
Yueh Z LeeDepartment of Physics and Astronomy, The University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0003-1846-7680
Rosa Tamara BrancaDepartment of Physics and Astronomy, The University of North Carolina, Chapel Hill, NC, USA.
Jennifer L GoralskiMarsico Lung Institute/UNC Cystic Fibrosis Center, The University of North Carolina, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Martina Gentzsch · 2004 to 2026
$26.5M
Quantitation and Spatial Registration of Airways Dysfunction with Dynamic 19F MRI in Cystic FibrosisK23HL138257 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORALSKI, JENNIFER L · 2020 to 2024
$1.0M
NCATS NIH HHS UL1 TR002489NHLBI NIH HHS K23 HL138257NIDDK NIH HHS P30 DK065988
6 · The paper itself

Abstract

purposeTo quantitatively compare dynamic

methodsTen participants with stable CF and a baseline FEV1 > 70% completed a single imaging session where dynamic

resultsVDP values from high-resolution

conclusionIn CF subjects, ventilation abnormalities are identified by both

Indexed as

Cystic FibrosisHumansLungMagnetic Resonance ImagingRespirationXenon IsotopesXenon Isotopescystic fibrosishyperpolarized gasperflorinated gas imagingVDPventilation defect

Identifiers

PMID32770779
PMCPMC7689687
OpenAlexW3048129807

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.