Evidence map›Paper›PMID 32770649›Full record

ArticleCancer reports (Hoboken, N.J.)2020

Evaluation of the clinical utility of maximum intensity projections of 3D contrast-enhanced, T1-weighted imaging for the detection of brain metastases.

Nicolin Hainc, Christian Federau, Anthony Tyndall, Andreas Mittermeier, Andrea Bink, Christoph Stippich, Tilman Schubert

Abstract readEvaluation Study
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicolin HaincDepartment of Medical Imaging, Division of Neuroradiology, Toronto Western Hospital, Toronto, Ontario, Canada.ORCID 0000-0003-0916-7387
Christian FederauDivision of Diagnostic and Interventional Neuroradiology, Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland.
Anthony TyndallDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Andreas MittermeierDepartment of Medical Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
Andrea BinkDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Christoph StippichDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Tilman SchubertDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo visualize and assess brain metastases on magnetic resonance imaging, radiologists face an ever-increasing pressure to perform faster and more efficiently. The usage of maximum intensity projections (MIPs) of contrast-enhanced T1-weighed (T1ce) magnetization-prepared rapid acquisition with gradient echo (MP-RAGE) images proposes to increase reading efficiency by increasing lesion conspicuity while reducing in the number of images to be reviewed.

aimTo assess if MIPs save reading time and achieve the same level of diagnostic accuracy as standard 1 mm T1ce images for the detection of brain metastases.

methodsForty-four patients were included in this retrospective study. Axial reformations of T1ce MP-RAGE (TR/TE = 2300/2.25 ms, resolution = 1 mm

resultsAbout 22.5 61.2 s/study and 43.8 ± 159.9 s/study were saved using 5 and 10 mm MIPs, respectively. Combined average sensitivity was 92.0% for 5 mm MIPs and 86.3% for 10 mm MIPs compared to standard 1 mm axial slices, with an average rate of 0.98 and 0.57 false positives per study, respectively

conclusionWhile 5 mm and 10 mm T1ce MP-RAGE MIPs showed a clinical benefit in reducing reading times for evaluation of brain metastases, they should be used in conjunction with standard 1 mm images for best sensitivity and specificity, a practice which possibly annuls their benefit.

Indexed as

Imaging, Three-DimensionalAdultAgedBrainBrain NeoplasmsContrast MediaDiffusion Magnetic Resonance ImagingFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityContrast MediaCNSmetastasesMR-imaging

Identifiers

PMID32770649
PMCPMC7941491

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.