Evidence map›Paper›PMID 32770385›Full record

ArticleObesity surgery2020

Reversal of Roux-en-Y Gastric Bypass Fails to Facilitate the Management of Recalcitrant Hypocalcaemia Caused by Primary Hypoparathyroidism.

Katrien Corbeels, Nele Steenackers, Matthias Lannoo, Ann Mertens, Ellen Deleus, Nelson Cunha, Pieter Sinonquel, Christophe Matthys, Ann Meulemans, Roman Vangoitsenhoven and 1 more

Open access · greenAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Katrien CorbeelsDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium. katrien.corbeels@kuleuven.be.ORCID http://orcid.org/0000-0001-9494-1650
Nele SteenackersDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium.
Matthias LannooDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium.
Ann MertensDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium.
Ellen DeleusDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium.
Nelson CunhaDepartment of Endocrinology, Coimbra Hospital and University Centre (CHUC), Coimbra, Portugal.
Pieter SinonquelDepartment of Translational Research in Gastrointestinal Disorders (TARGID), KU Leuven, Leuven, Belgium.
Christophe MatthysDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium.
Ann MeulemansDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium.
Roman VangoitsenhovenDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium.
Bart Van der SchuerenDepartment of Chronic diseases, Metabolism & Ageing (CHROMETA), Clinical and Experimental Endocrinology, KU Leuven, O&N1 Herestraat 49 - box 902, 3000, Leuven, Belgium.
KU Leuven · BEUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Roux-en-Y gastric bypass (RYGB) is thought to reduce calcium absorption from the gut. Here, we report the case of a patient with a RYGB, who developed primary hypoparathyroidism after a total thyroidectomy, leading to recalcitrant hypocalcaemia. Despite aggressive oral calcium and calcitriol supplementation, she remained hypocalcaemic and required intravenous (IV) calcium supplementation to control her symptoms, and to keep calcium serum levels within an acceptable range. Teriparatide treatment improved calcium levels marginally. This treatment, however, was poorly tolerated and ultimately stopped by the patient. As a last resort, reversal of RYGB was performed to improve calcium absorption from the gut. Unfortunately, IV calcium supplementation remained necessary. This case illustrates that the reversal of RYGB is not always a guarantee for success in managing recalcitrant hypocalcaemia.

Indexed as

Gastric BypassHypocalcemiaHypoparathyroidismObesity, MorbidFemaleHumansThyroidectomyBariatric surgeryCalciumParathyroid hormoneRoux-en-Y gastric bypassThyroidectomy

Identifiers

PMID32770385
OpenAlexW3048215846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.