ArticleScientific reports2020
Thyroid cancer diagnosis by Raman spectroscopy.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Raman Spectroscopy as a Potential Adjunct of Thyroid Nodule Evaluation: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Review
- Recent advances in applications of artificial intelligence-assisted Raman spectroscopy in diagnosis of cancers.Frontiers in molecular biosciences · 2025Review
- Is Raman Spectroscopy of Fingernails a Promising Tool for Diagnosing Systemic and Dermatological Diseases in Adult and Pediatric Populations?Medicina (Kaunas, Lithuania) · 2024Review
- Label-Free Surface-Enhanced Raman Spectroscopy with Machine Learning for the Diagnosis of Thyroid Cancer by Using Fine-Needle Aspiration Liquid Samples.Biosensors · 2024Article
- Raman-Based Techniques in Medical Applications for Diagnostic Tasks: A Review.International journal of molecular sciences · 2023Review
- An eXplainable Artificial Intelligence analysis of Raman spectra for thyroid cancer diagnosis.Scientific reports · 2023Article
- Auxiliary Diagnosis of Papillary Thyroid Carcinoma Based on Spectral Phenotype.Phenomics (Cham, Switzerland) · 2023Article
- Biomineralogical signatures of breast microcalcifications.Science advances · 2023Article
- Fast and Deep Diagnosis Using Blood-Based ATR-FTIR Spectroscopy for Digestive Tract Cancers.Biomolecules · 2022Article
- Unraveling the Effects of Carotenoids Accumulation in Human Papillary Thyroid Carcinoma.Antioxidants (Basel, Switzerland) · 2022Article
- Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review.Metabolites · 2022Review
- Rapid label-free detection of cholangiocarcinoma from human serum using Raman spectroscopy.PloS one · 2022Article
- Recent Advances in the Label-Free Characterization of Exosomes for Cancer Liquid Biopsy: From Scattering and Spectroscopy to Nanoindentation and Nanodevices.Nanomaterials (Basel, Switzerland) · 2021Review
- Spectroscopic evaluation of carcinogenesis in endometrial cancer.Scientific reports · 2021Article
- Malignant and benign thyroid nodule differentiation through the analysis of blood plasma with terahertz spectroscopy.Biomedical optics express · 2021Article
- Raman Spectroscopy Discloses Altered Molecular Profile in Thyroid Adenomas.Diagnostics (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last 50 years, the incidence of human thyroid cancer disease has seen a significative increment. This comes along with an even higher increment of surgery, since, according to the international guidelines, patients are sometimes addressed to surgery also when the fine needle aspiration gives undetermined cytological diagnosis. As a matter of fact, only 30% of the thyroid glands removed for diagnostic purpose have a post surgical histological report of malignancy: this implies that about 70% of the patients have suffered an unnecessary thyroid removal. Here we show that Raman spectroscopy investigation of thyroid tissues provides reliable cancer diagnosis. Healthy tissues are consistently distinguished from cancerous ones with an accuracy of [Formula: see text] 90%, and the three cancer typology with highest incidence are clearly identified. More importantly, Raman investigation has evidenced alterations suggesting an early stage of transition of adenoma tissues into cancerous ones. These results suggest that Raman spectroscopy may overcome the limits of current diagnostic tools.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.