Evidence map›Paper›PMID 32769426›Full record

GuidelineThe American journal of gastroenterology2020

ACG Clinical Guidelines: Clinical Use of Esophageal Physiologic Testing.

C Prakash Gyawali, Dustin A Carlson, Joan W Chen, Amit Patel, Robert J Wong, Rena H Yadlapati

Open access · greenAbstract readPractice Guideline
In one paragraph

Guideline in The American journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 4 pooled it
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 4 syntheses or guidelines pooled it, 180 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. AGA Clinical Practice Update on the Personalized Approach to the Evaluation and Management of GERD: Expert Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Guideline
  4. Use of the Functional Lumen Imaging Probe in Clinical Esophagology.The American journal of gastroenterology · 2020
    Guideline
  5. Review
  6. Article
  7. Utilization trends for esophageal motility testing in the United States.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Diagnostic value of real-time dynamic gastric contrast ultrasound for hiatal hernia.Hernia : the journal of hernias and abdominal wall surgery · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

C Prakash GyawaliDivision of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, USA.
Dustin A CarlsonDivision of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Joan W ChenDepartment of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
Amit PatelDivision of Gastroenterology, Duke University & Durham VA Medical Center, Durham, North Carolina, USA.
Robert J WongDepartment of Internal Medicine, Alameda Health System-Highland Hospital, Oakland, California, USA.
Rena H YadlapatiDivision of Gastroenterology and Hepatology, University of California in San Diego, La Jolla, California, USA.
Duke University · USHighland Hospital · USNorthwestern University · USUniversity of Michigan–Ann Arbor · USWashington University in St. Louis · US

Funding

Role of altered response to volumetric distension in esophageal diseaseP01DK117824 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2018 to 2022
$7.3M
NIDDK NIH HHS P01 DK117824
6 · The paper itself

Abstract

Esophageal symptoms are common and may indicate the presence of gastroesophageal reflux disease (GERD), structural processes, motor dysfunction, behavioral conditions, or functional disorders. Esophageal physiologic tests are often performed when initial endoscopic evaluation is unrevealing, especially when symptoms persist despite empiric management. Commonly used esophageal physiologic tests include esophageal manometry, ambulatory reflux monitoring, and barium esophagram. Functional lumen imaging probe (FLIP) has recently been approved for the evaluation of esophageal pressure and dimensions using volumetric distension of a catheter-mounted balloon and as an adjunctive test for the evaluation of symptoms suggestive of motor dysfunction. Targeted utilization of esophageal physiologic tests can lead to definitive diagnosis of esophageal disorders but can also help rule out organic disorders while making a diagnosis of functional esophageal disorders. Esophageal physiologic tests can evaluate obstructive symptoms (dysphagia and regurgitation), typical and atypical GERD symptoms, and behavioral symptoms (belching and rumination). Certain parameters from esophageal physiologic tests can help guide the management of GERD and predict outcomes. In this ACG clinical guideline, we used the Grading of Recommendations Assessment, Development and Evaluation process to describe performance characteristics and clinical value of esophageal physiologic tests and provide recommendations for their utilization in routine clinical practice.

Indexed as

Deglutition DisordersEsophageal pH MonitoringEsophagoscopyEsophagusGastroesophageal RefluxHumansManometry

Identifiers

PMID32769426
PMCPMC9468980
OpenAlexW3048384049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.