Evidence map›Paper›PMID 32769119›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

A Point Mutation Creating a 3' Splice Site in

Peter Densen, Laynez Ackermann, Leslie Saucedo, Julio E Figueroa, Zhi-Hai Si, Conrad Martin Stoltzfus

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Peter DensenDepartment of Internal Medicine, Veteran Affairs Medical Center and University of Iowa College of Medicine, Iowa City, IA 52242; peter-densen@uiowa.edu.
Laynez AckermannDepartment of Microbiology and Immunology, University of Iowa College of Medicine, Iowa City, IA 52242.
Leslie SaucedoDepartment of Biology, University of Puget Sound, Tacoma, WA 98416.
Julio E FigueroaDepartment of Internal Medicine, Section of Infectious Diseases, Louisiana State University, New Orleans, LA 70112; and.ORCID 0000-0002-8716-7465
Zhi-Hai SiAkebia Therapeutics, Cambridge, MA 02142.
Conrad Martin StoltzfusDepartment of Microbiology and Immunology, University of Iowa College of Medicine, Iowa City, IA 52242.
University of Iowa · USAkebia Therapeutics (United States) · USLouisiana State University · USUniversity of Puget Sound · US

Funding

REGULATION OF HIV-1 RNA SPLICINGR01AI036073 · NIAID · UNIVERSITY OF IOWA · PI AMENDT, BRAD · 1995 to 2010
$2.5M
Regulation of HIV-1 RNA SplicingR56AI036073 · NIAID · UNIVERSITY OF IOWA · PI STOLTZFUS, CONRAD · 2005 to 2005
$332k
RETROVIRUS RNA METABOLISMR01CA028051 · NCI · UNIVERSITY OF IOWA · PI STOLTZFUS, CONRAD · 1985 to 1999
–
NCI NIH HHS R01 CA028051NIAID NIH HHS R01 AI036073NIAID NIH HHS R56 AI036073
6 · The paper itself

Abstract

C8α-γ deficiency was examined in four unrelated African Americans. Two individuals were compound heterozygotes for a previously reported point mutation in exon 9. mRNA from the remaining six

Indexed as

Black or African AmericanAllelesComplement C8Genetic Association StudiesHeterozygoteHumansImmunologic Deficiency SyndromesPoint MutationProtein SplicingRNA, MessengerRNA Splice SitesSequence Analysis, DNAComplement C8RNA, MessengerRNA Splice Sites

Identifiers

PMID32769119
PMCPMC7484158
OpenAlexW3048208046

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.