Evidence map›Paper›PMID 32769099›Full record

ArticleGenetics2020

Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control.

Yang Hu, Alejandra Korovaichuk, Mariana Astiz, Henning Schroeder, Rezaul Islam, Jon Barrenetxea, Andre Fischer, Henrik Oster, Henrik Bringmann

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Gene-by-Sleep Duration Interaction for Glycemic Traits in over 480,000 Individuals.medRxiv : the preprint server for health sciences · 2026
    Article
  5. Current Evidence for Sleep States inCurrent sleep medicine reports · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Orthologs ofSleep advances : a journal of the Sleep Research Society · 2024
    Article
  13. Article
  14. A conserved role forSleep advances : a journal of the Sleep Research Society · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Intracellular CaiScience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yang HuMax Planck Research Group "Sleep and Waking", Max Planck Institute for Biophysical Chemistry, Göttingen 37077, Germany.ORCID 0000-0002-2515-4458
Alejandra KorovaichukMax Planck Research Group "Sleep and Waking", Max Planck Institute for Biophysical Chemistry, Göttingen 37077, Germany.
Mariana AstizInstitute of Neurobiology, University of Lübeck, 23562, Germany.ORCID 0000-0001-9912-1686
Henning SchroederGerman Center for Neurodegenerative Diseases, Göttingen 37075, Germany.
Rezaul IslamGerman Center for Neurodegenerative Diseases, Göttingen 37075, Germany.
Jon BarrenetxeaMax Planck Research Group "Sleep and Waking", Max Planck Institute for Biophysical Chemistry, Göttingen 37077, Germany.
Andre FischerGerman Center for Neurodegenerative Diseases, Göttingen 37075, Germany.
Henrik OsterInstitute of Neurobiology, University of Lübeck, 23562, Germany.ORCID 0000-0002-1414-7068
Henrik BringmannMax Planck Research Group "Sleep and Waking", Max Planck Institute for Biophysical Chemistry, Göttingen 37077, Germany Henrik.Bringmann@mpibpc.mpg.de.ORCID 0000-0002-7689-8617
Max Planck Institute for Biophysical Chemistry · DEGerman Center for Neurodegenerative Diseases · DEUniversity of Lübeck · DEUniversity of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep is a conserved behavioral state. Invertebrates typically show quiet sleep, whereas in mammals, sleep consists of periods of nonrapid-eye-movement sleep (NREMS) and REM sleep (REMS). We previously found that the transcription factor AP-2 promotes sleep in

Indexed as

Sleep StagesAnimalsCircadian RhythmDelta RhythmMemoryMiceSleep DeprivationTheta RhythmTranscription Factor AP-2Tfap2a protein, mouseTfap2b protein, mouseTranscription Factor AP-2behaviorEEGMus musculussleepTFAP2

Identifiers

PMID32769099
PMCPMC7648577
OpenAlexW3048286924

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.