Evidence map›Paper›PMID 32768663›Full record

ArticleCellular immunology2020

Bcl10 is associated with actin dynamics at the T cell immune synapse.

Kaustubh Wagh, Brittany A Wheatley, Maria K Traver, Imran Hussain, Brian C Schaefer, Arpita Upadhyaya

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Super-Resolution Imaging Approaches for Quantifying F-Actin in Immune Cells.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kaustubh WaghDepartment of Physics, University of Maryland, College Park, MD 20742, USA.
Brittany A WheatleyInstitute for Physical Science and Technology, University of Maryland, College Park, MD 20742, USA.
Maria K TraverDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA.
Imran HussainDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA.
Brian C SchaeferDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD 20814, USA.
Arpita UpadhyayaDepartment of Physics, University of Maryland, College Park, MD 20742, USA; Institute for Physical Science and Technology, University of Maryland, College Park, MD 20742, USA. Electronic address: arpitau@umd.edu.
Uniformed Services University of the Health Sciences · USUniversity of Maryland, College Park · US

Funding

T cell receptor-activated autophagy as a regulator of T cell effector responsesR01AI125552 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI CONRADS, THOMAS PATRICK, HE, YOU-WEN · 2017 to 2021
$3.1M
Supplement request for Microtubule regulation of actomyosin dynamics and force generation in T lymphocytesR01GM131054 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI UPADHYAYA, ARPITA · 2019 to 2022
$1.4M
Elucidating TCR signaling mechanisms via quantitative pattern analysis_administrative supplementU01GM109887 · NIGMS · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI LOSERT, WOLFGANG, SCHAEFER, BRIAN · 2014 to 2017
$1.1M
NIAID NIH HHS R01 AI125552NIGMS NIH HHS R01 GM131054NIGMS NIH HHS U01 GM109887
6 · The paper itself

Abstract

T cell responses to antigen are initiated by engagement of the T cell receptor (TCR)

Indexed as

ActinsAnimalsB-Cell CLL-Lymphoma 10 ProteinMaleMiceMice, Inbred C57BLMucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinNF-kappa BPhosphorylationReceptors, Antigen, T-CellSignal TransductionSynapsesActinsB-Cell CLL-Lymphoma 10 ProteinBcl10 protein, mouseMucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinNF-kappa BReceptors, Antigen, T-CellActin dynamicsBcl10Immune synapseNF-κBT cell activationTIRF microscopy

Identifiers

PMID32768663
PMCPMC7846448
OpenAlexW3042439749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.