Evidence map›Paper›PMID 32768431›Full record

ArticleAmerican journal of obstetrics and gynecology2021

Fetal growth velocity standards from the Fetal Growth Longitudinal Study of the INTERGROWTH-21

Eric O Ohuma, José Villar, Yuan Feng, Luo Xiao, Laurent Salomon, Fernando C Barros, Leila Cheikh Ismail, William Stones, Yasmin Jaffer, Manuela Oberto and 11 more

Abstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  6. Foetal growth in pregnant women with HIV.AIDS (London, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Eric O OhumaCentre for Tropical Medicine and Global Health, Headington, Oxford, United Kingdom; Maternal, Adolescent, Reproductive & Child Health (MARCH) Centre, London School of Hygiene & Tropical Medicine (LSHTM), London, United Kingdom. Electronic address: eric.ohuma@ndm.ox.ac.uk.
José VillarNuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom; Oxford Maternal & Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, United Kingdom.
Yuan FengDepartment of Statistics, North Carolina State University, Raleigh, NC.
Luo XiaoDepartment of Statistics, North Carolina State University, Raleigh, NC.
Laurent SalomonDepartment of Obstetrics and Fetal Medicine, Hôpital Necker Enfants Malades, Université Paris Descartes, Paris, France.
Fernando C BarrosPrograma de Pós-Graduação em Saúde e Comportamento, Universidade Católica de Pelotas, Pelotas, Brazil.
Leila Cheikh IsmailNuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom; Clinical Nutrition and Dietetics Department, University of Sharjah, Sharjah, United Arab Emirates.
William StonesFaculty of Health Sciences, Aga Khan University, Nairobi, Kenya.
Yasmin JafferDepartment of Family & Community Health, Ministry of Health, Muscat, Sultanate of Oman.
Manuela ObertoS.C. Ostetricia 2U, Città della Salute e della Scienza di Torino, Italy.
J Alison NobleDepartment of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom.
Michael G GravettDepartments of Obstetrics & Gynecology and Public Health, University of Washington, Seattle, WA.
Qingqing WuDepartment of Ultrasound, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
Cesar G VictoraPrograma de Pós-Graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil.
Ann LambertNuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom.
Paola Di NicolaDipartimento di Scienze Pediatriche e dell' Adolescenza, Terapia Intensiva Neonatale Ospedale (TINO), Torino, Italy.
Manorama PurwarNagpur INTERGROWTH-21st Research Centre, Ketkar Hospital, Nagpur, India.
Zulfiqar A BhuttaCenter for Global Child Health, Hospital for Sick Children, Toronto, Canada.
Stephen H KennedyNuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom; Oxford Maternal & Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, United Kingdom.
Aris T PapageorghiouNuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom; Oxford Maternal & Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, United Kingdom.
International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st Project)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman growth is susceptible to damage from insults, particularly during periods of rapid growth. Identifying those periods and the normative limits that are compatible with adequate growth and development are the first key steps toward preventing impaired growth.

objectiveThis study aimed to construct international fetal growth velocity increment and conditional velocity standards from 14 to 40 weeks' gestation based on the same cohort that contributed to the INTERGROWTH-21 STUDY

designThis study was a prospective, longitudinal study of 4321 low-risk pregnancies from 8 geographically diverse populations in the INTERGROWTH-21

resultsPeak velocity was observed at a similar gestational age: 16 and 17 weeks' gestation for head circumference (12.2 mm/wk), and 16 weeks' gestation for abdominal circumference (11.8 mm/wk) and femur length (3.2 mm/wk). However, velocity growth slowed down rapidly for head circumference, biparietal diameter, occipitofrontal diameter, and femur length, with an almost linear reduction toward term that was more marked for femur length. Conversely, abdominal circumference velocity remained relatively steady throughout pregnancy. The change in velocity with gestational age was more evident for head circumference, biparietal diameter, occipitofrontal diameter, and femur length than for abdominal circumference when the change was expressed as a percentage of fetal size at 40 weeks' gestation. We have also shown how to obtain accurate conditional fetal velocity based on our previous methodological work.

conclusionThe fetal skeleton and abdomen have different velocity growth patterns during intrauterine life. Accordingly, we have produced international Fetal Growth Velocity Increment Standards to complement the INTERGROWTH-21

Indexed as

Fetal DevelopmentGestational AgeAbdomenAdultCrown-Rump LengthFemaleFemurGrowth ChartsHeadHumansInfant, NewbornInternationalityLongitudinal StudiesMalePregnancyUltrasonography, Prenatalcorrelation modelsfetal growthfetal growth velocityfetal velocity standardslongitudinal study

Identifiers

PMID32768431
PMCPMC7858163

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.