ReviewJornal de pediatria
COVID-19 and obesity in childhood and adolescence: a clinical review.
Review in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04799132 (Association Between Body Mass Index and High-flow Cannula Therapy Success in Patients With Severe Covid 19 Related Pneumonia. Retrospective Study.), which is not on this map. Cited by 97 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association Between Body Mass Index and High-flow Cannula Therapy Success in Patients With Severe Covid 19 Related Pneumonia. Retrospective Study.
Who cites it
97 citing papers in PubMed, 1 synthesis or guideline pooled it, 230 citations in OpenAlex.
- Obesity and COVID-19 in Children and Adolescents: Reciprocal Detrimental Influence-Systematic Literature Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Impact of COVID-19 on childhood obesity: Data from a paediatric weight management trial.Pediatric obesity · 2022Trial
- Clinical (BMI and MRI) and Biochemical (Adiponectin, Leptin, TNF-α, and IL-6) Effects of High-Intensity Aerobic Training with High-Protein Diet in Children with Obesity Following COVID-19 Infection.International journal of environmental research and public health · 2022Trial
- Article
- Effect of Abdominal Adiposity on the Impact of Plantar Force in the Foot Support of Obese and Overweight Schoolchildren.Children (Basel, Switzerland) · 2025Article
- Association between the Body Roundness Index and spirometric parameters among U.S. Adolescents from NHANES 2007-2012.BMC pulmonary medicine · 2025Article
- Clinical characteristics and burden of COVID-19 in children and adolescents in Colombia: a retrospective database analysis.BMJ paediatrics open · 2025Article
- Lessons learned from the COVID-19 pandemic on the global health needs of young children: A cross-sectional study.Anales del sistema sanitario de Navarra · 2025Article
- Physical fitness and body build parameters of children and adolescents participating in the physical activity promotion programme "Athletics for all!"Archives of public health = Archives belges de sante publique · 2024Article
- Obesity as a Risk Factor for the Severity of COVID-19 in Pediatric Patients: Possible Mechanisms-A Narrative Review.Children (Basel, Switzerland) · 2024Review
- Exploring the Link between Oxidative Stress, Selenium Levels, and Obesity in Youth.International journal of molecular sciences · 2024Review
- Hedonic hunger, food addiction, and night eating syndrome triangle in adolescents and ıts relationship with body mass ındex.Journal of eating disorders · 2024Article
- Article
- Clinical characteristics of COVID-19 in children: a large multicenter study from Iran.Frontiers in pediatrics · 2024Article
- Study on the relationship between body mass index and blood pressure indices in children aged 7-17 during COVID-19.Frontiers in public health · 2024Article
- Multisystem inflammatory syndrome in 1.2 million children: longitudinal cohort study of risk factors.Pediatric research · 2024Article
- Evaluating the impact of childhood BMI on the risk of coronavirus disease 2019: A Mendelian randomization study.Open medicine (Warsaw, Poland) · 2024Article
- Effect of an educational intervention on diet and physical activity among school-aged adolescents in Delhi -The i-PROMISe (PROMoting health literacy in Schools) Plus Study.Dialogues in health · 2023Article
- Interdisciplinary Therapy Improves the Mediators of Inflammation and Cardiovascular Risk in Adolescents with Obesity.International journal of environmental research and public health · 2023Article
- Promoting Health in Pediatric Obesity: A Decade's Research of Physical Activity's Influence on Cardiometabolic Parameters.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify factors that contribute to the increased susceptibility and severity of COVID-19 in obese children and adolescents, and its health consequences. SOURCES: Studies published between 2000 and 2020 in the PubMed, MEDLINE, Scopus, SciELO, and Cochrane databases. SUMMARY OF
findingsObesity is a highly prevalent comorbidity in severe cases of COVID-19 in children and adolescents; social isolation may lead to increase fat accumulation. Excessive adipose tissue, deficit in lean mass, insulin resistance, dyslipidemia, hypertension, high levels of proinflammatory cytokines, and low intake of essential nutrients are factors that compromise the functioning of organs and systems in obese individuals. These factors are associated with damage to immune, cardiovascular, respiratory, and urinary systems, along with modification of the intestinal microbiota (dysbiosis). In severe acute respiratory syndrome coronavirus 2 infection, these organic changes from obesity may increase the need for ventilatory assistance, risk of thromboembolism, reduced glomerular filtration rate, changes in the innate and adaptive immune response, and perpetuation of the chronic inflammatory response.
conclusionsThe need for social isolation can have the effect of causing or worsening obesity and its comorbidities, and pediatricians need to be aware of this issue. Facing children with suspected or confirmed COVID-19, health professionals should 1) diagnose excess weight; 2) advise on health care in times of isolation; 3) screen for comorbidities, ensuring that treatment is not interrupted; 4) measure levels of immunonutrients; 5) guide the family in understanding the specifics of the situation; and 6) refer to units qualified to care for obese children and adolescents when necessary.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.