Evidence map›Paper›PMID 32767906›Full record

ArticleCurrent eye research2021

The Effect of Software Versions on the Measurement of Retinal Vascular Densities Using Optical Coherence Tomography Angiography.

Huijuan Wang, Huiling Hu, Giovanni Gregori, Juan Zhang, Hong Jiang, Jianhua Wang

Open access · greenAbstract read
In one paragraph

Article in Current eye research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Evaluation of childhood developingWorld journal of clinical cases · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Huijuan WangDepartment of Ophthalmology, Eye Hospital, China Academy of Chinese Medical Sciences , Beijing, China.
Huiling HuDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine , Miami, FL, USA.
Giovanni GregoriDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine , Miami, FL, USA.
Juan ZhangDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine , Miami, FL, USA.
Hong JiangDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine , Miami, FL, USA.
Jianhua WangDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine , Miami, FL, USA.
University of Miami · USChinese Academy of Medical Sciences & Peking Union Medical College · CNJinan University · CN

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dmitry V Ivanov · 2004 to 2026
$12.2M
Novel Biomarkers of Small Vessel Contributions to Vascular Cognitive Impairment and Dementia (VCID)R01NS111115 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DETRE, JOHN A, WANG, JIANHUA · 2019 to 2023
$3.7M
NEI NIH HHS P30 EY014801NINDS NIH HHS R01 NS111115
6 · The paper itself

Abstract

backgroundThe goal of the study was to determine the effect of different software versions on the measurement of retinal vessel densities using optical coherence tomography angiography (OCTA) in normal subjects.

methodsThirty-two eyes of eighteen healthy subjects were imaged using two OCTA devices: the Optovue RTVue and the Zeiss Cirrus. The macular 3 × 3 mm scan protocol was used. The images acquired using the Optovue OCTA device were exported using two different software versions in the system and compared to the images acquired through the Zeiss OCTA. In addition, the Optovue OCTA images were exported after manual adjustment of the segmentation boundaries according to the intraretinal layer definition. The densities of the superficial vascular plexus (SVP) and deep vascular plexus (DVP) were measured using fractal analysis by box-counting (Dbox).

resultsBoth the vessel densities of the SVP and DVP acquired using the Optovue OCTA device were significantly different when compared to those from the Zeiss OCTA device (all,

conclusionThis is the first study to determine that different software versions with various intraretinal layer segmentation methods affect the vessel density measurements of the SVP and DVP.

Indexed as

SoftwareAdultDiagnosis, Computer-AssistedFemaleFluorescein AngiographyFundus OculiHumansMaleMicrovascular DensityMiddle AgedProspective StudiesRetinal VesselsTomography, Optical CoherenceYoung Adultdeep vascular plexus (DVP)optical coherence tomography angiography (OCTA)segmentationsoftware versionsuperficial vascular plexus (SVP)Vessel density

Identifiers

PMID32767906
PMCPMC7878200
OpenAlexW3047756083

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.