Evidence map›Paper›PMID 32767718›Full record

ArticleJournal of veterinary internal medicine2020

Echocardiographic predictors of first onset of atrial fibrillation in dogs with myxomatous mitral valve disease.

Marco Baron Toaldo, Chiara Mazzoldi, Giovanni Romito, Helen Poser, Barbara Contiero, Mario Cipone, Carlo Guglielmini

Open access · goldAbstract readObservational Study, Veterinary
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Evaluation of Galectin-3 in Dogs with Atrial Fibrillation.Animals : an open access journal from MDPI · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Prevalence of sudden cardiac death in dogs with atrial fibrillation.Journal of veterinary internal medicine · 2021
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Marco Baron ToaldoDepartment of Veterinary Medical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0001-9609-1856
Chiara MazzoldiDepartment of Veterinary Medical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Giovanni RomitoDepartment of Veterinary Medical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Helen PoserDepartment of Animal Medicine, Production and Health, University of Padova, Padua, Italy.
Barbara ContieroDepartment of Animal Medicine, Production and Health, University of Padova, Padua, Italy.
Mario CiponeDepartment of Veterinary Medical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Carlo GuglielminiDepartment of Animal Medicine, Production and Health, University of Padova, Padua, Italy.ORCID https://orcid.org/0000-0001-7575-3646
University of Bologna · ITUniversity of Padua · ITUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) occurs in dogs with myxomatous mitral valve disease (MMVD) as a consequence of left atrial (LA) dilatation, and it affects survival and quality of life.

objectivesTo evaluate the usefulness of echocardiography in predicting the first occurrence of AF in dogs with MMVD. ANIMALS: Forty-four client-owned dogs with MMVD, 22 dogs that developed AF, and 22 dogs that maintained sinus rhythm.

methodsRetrospective observational study. Medical databases were reviewed for dogs that developed AF during the year after diagnosis of MMVD (AF group). The last echocardiographic examination obtained while still in sinus rhythm was used to derive selected variables. For each dog with AF, a control dog matched for body weight, class of heart failure, and LA dimension was selected. Echocardiographic results including LA volumes and LA speckle tracking echocardiography (STE)-derived variables were measured.

resultsAmong the tested echocardiographic variables, only LA diameter (P = .03) and left ventricular internal diameter in diastole (P = .03) differed significantly between groups, whereas body weight-indexed variables of cardiac dimension as well as LA volumes and volume-derived functional variables were not different. Among the STE-derived variables, peak atrial longitudinal strain (PALS) results differed significantly between the AF group (23.8% ± 8.6%) and the control group (30.5% ± 9.6%; P = .03). A value of PALS ≤28% predicted AF occurrence with sensitivity and specificity of 0.80 and 0.65, respectively. CONCLUSIONS AND CLINICAL IMPORTANCE: Absolute cardiac diameters and LA STE (in particular, PALS) are useful echocardiographic predictors for the development of AF in dogs with MMVD.

Indexed as

Atrial FibrillationDog DiseasesAnimalsAtrial Function, LeftDogsEchocardiographyMitral ValveQuality of Lifecanineleft atriumspeckle tracking echocardiographystrain

Identifiers

PMID32767718
PMCPMC7517854
OpenAlexW3048081375

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.