Evidence map›Paper›PMID 32767180›Full record

Observational studyHernia : the journal of hernias and abdominal wall surgery2020

A new semiresorbable mesh for primary inguinal repair: a preliminary observational study on quality of life and safety.

D Greco, G Santori, G Brancato, F Gossetti, P L Ipponi, P Negro, E Gianetta, S C Giovannini, M Mascherini, C Stabilini

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Hernia : the journal of hernias and abdominal wall surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

D GrecoNiguarda Hospital IRCCS, Milan, Italy.
G SantoriDepartment of Surgical Sciences (DISC), University of Genoa, Policlinico San Martino IRCCS, Genoa, Italy.
G BrancatoDepartment of Surgery, Policlinico Vittorio Emanuele, P.O. G. Rodolico, Catania, Italy.
F GossettiDepartment of Surgery "P. Stefanini", Sapienza University, Rome, Italy.
P L IpponiGeneral Surgery Unit, San Giovanni di Dio Hospital, Florence, Italy.
P NegroDepartment of Surgery "P. Stefanini", Sapienza University, Rome, Italy.
E GianettaDepartment of Surgical Sciences (DISC), University of Genoa, Policlinico San Martino IRCCS, Genoa, Italy.
S C GiovanniniDepartment of Surgical Sciences (DISC), University of Genoa, Policlinico San Martino IRCCS, Genoa, Italy.
M MascheriniDepartment of Surgical Sciences (DISC), University of Genoa, Policlinico San Martino IRCCS, Genoa, Italy.
C StabiliniDepartment of Surgical Sciences (DISC), University of Genoa, Policlinico San Martino IRCCS, Genoa, Italy. cesarestabil@hotmail.com.ORCID 0000-0002-5410-0352
Ospedale Policlinico San Martino · ITSapienza University of Rome · ITAzienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITNuovo Ospedale San Giovanni di Dio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA currently unsolved problem of open inguinal hernia repair (IHR) is chronic postoperative inguinal pain (CPIP), which affects 10-12% of patients after IHR. In the present paper, we explored the results of a newly designed partially absorbable mesh made of polypropylene and polylactic acid (HybridMesh

methodsA prospective multicentric pilot trial was conducted in third-referral centers across Italy (n = 5). Inclusion criteria were unilateral primary inguinal hernia in patients of both genders and BMI < 30 kg/m

resultsBetween 2015 and 2016, 125 (5 female) patients were operated, 2-year follow-up rate was 100%. The surgical site occurrence rate was 28% without the need of procedural interventions. Twenty-four months after surgery, no case of severe CPIP was recorded and altered global CCS score was present in 16 patients (13.0%). At univariate analysis, CCS score was negatively affected by fixation with sutures (OR 3.949; 95% CI 1.334-13.300), with no effect shown on multivariate analysis. Alterations in pain and movement limitations domains of CCS were observed in 9.7% of patients, at univariate analysis; they occurred more frequently when the mesh was sutured (OR 4.437; 95% CI 1.387-17.025) and in patients suffering from SSO (ecchymosis: OR 3.269; 95% CI 1.032-10.405); however, no effect was shown on multivariate analysis. Two recurrences (1.6%) were identified within the first postoperative year.

conclusionsThe results of this study support the safety, efficacy and good tolerability of HybridMesh as a device to treat primary unilateral inguinal hernia during open anterior approach. Further studies are needed to clarify its role in comparison to currently available devices at longer follow-ups.

Indexed as

FemaleHernia, InguinalHerniorrhaphyHumansMalePilot ProjectsProspective StudiesQuality of LifeSurgical MeshCarolina Comfort ScaleHybridMeshInguinal herniaMaterialsMesh

Identifiers

PMID32767180
OpenAlexW3047714062

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.