Evidence map›Paper›PMID 32767135›Full record

SynthesisClinical and experimental nephrology2020

Extracellular vesicles carrying miRNAs in kidney diseases: a systemic review.

Wei Zhang, Bin Yi, Shi-Kun Yang, Aimei Li, Jianwen Wang, Hao Zhang

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical and experimental nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei ZhangDepartment of Nephrology, Central South University, Hunan, The Third Xiangya HospitalNo.138 Tongzipo Road, Changsha, 410013, China.ORCID http://orcid.org/0000-0001-8679-6713
Bin YiDepartment of Nephrology, Central South University, Hunan, The Third Xiangya HospitalNo.138 Tongzipo Road, Changsha, 410013, China.
Shi-Kun YangDepartment of Nephrology, Central South University, Hunan, The Third Xiangya HospitalNo.138 Tongzipo Road, Changsha, 410013, China.
Aimei LiDepartment of Nephrology, Central South University, Hunan, The Third Xiangya HospitalNo.138 Tongzipo Road, Changsha, 410013, China.
Jianwen WangDepartment of Nephrology, Central South University, Hunan, The Third Xiangya HospitalNo.138 Tongzipo Road, Changsha, 410013, China.
Hao ZhangDepartment of Nephrology, Central South University, Hunan, The Third Xiangya HospitalNo.138 Tongzipo Road, Changsha, 410013, China. zhanghaoliaoqing@163.com.ORCID http://orcid.org/0000-0002-2049-3485

Funding

National Natural Science Foundation of China 81870498National Natural Science Foundation of China 81900633
6 · The paper itself

Abstract

MiRNAs play essential roles in processes of physiological status and disease conditions including in renal diseases, while extracellular vesicles (EVs) serve as important mediators for cell-cell communication. In body fluid or extracellular spaces, miRNAs are packaged into EVs and transferred to targeted cells to perform their bioeffects under particular conditions. In the present review, we aim to summarize and update the known and verified EV-carrying miRNAs (EV-miRNAs) and their general roles in kidney diseases. In addition to performing a systemic analysis, we try to provide some clues and perspectives for the future study of EV-miRNAs in renal diseases.

Indexed as

AnimalsBiomarkersExtracellular VesiclesGene Expression RegulationHumansKidneyKidney DiseasesMicroRNAsPrognosisBiomarkersMicroRNAsExosomeExtracellular vesiclesKidney diseasemicroRNASystemic review

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.