SynthesisArchives of women's mental health2021
The role of prenatal and perinatal factors in eating disorders: a systematic review.
Synthesis in Archives of women's mental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Treatment of eating disorders: A systematic meta-review of meta-analyses and network meta-analyses.Neuroscience and biobehavioral reviews · 2022Pooled it
- Maternal Gestational Low-Grade Inflammation and the Risk of Anorexia Nervosa in Daughters.The International journal of eating disorders · 2026Article
- Gestational High-Fat Diet Drives Premature Differentiation of Orexigenic Neurons and Reactivity of Astrocytes in the Fetal Rat Lateral Hypothalamus.Brain sciences · 2025Article
- Transgenerational transmission of eating disorders: the role of eating disorder symptoms and socio-cultural attitudes.Journal of eating disorders · 2025Article
- Perinatal risk factors and disordered eating in children and adolescents.Eating and weight disorders : EWD · 2025Article
- Exploring the Relationship Between Eating Disorders and Reproductive Health, with a Focus on Fertility, Obstetric, and Fetal Outcomes: A Narrative Review.Current nutrition reports · 2025Review
- Early intervention in eating disorders: introducing the chronopathogram.Eating and weight disorders : EWD · 2025Review
- Two identical twin pairs discordant for longstanding anorexia nervosa and OSFED: lived experience accounts of eating disorder and recovery processes.Journal of eating disorders · 2024Article
- Interplay of polygenic liability with birth-related, somatic, and psychosocial factors in anorexia nervosa risk: a nationwide study.Psychological medicine · 2024Article
- Birth-related, medical, and diagnostic characteristics in younger versus older children with avoidant/restrictive food intake disorder (ARFID).Journal of eating disorders · 2023Article
- Risk factors for eating disorders: findings from a rapid review.Journal of eating disorders · 2023Review
- The early life course-related traits with three psychiatric disorders: A two-sample Mendelian randomization study.Frontiers in psychiatry · 2023Article
- Mechanisms by which adverse childhood experiences, other traumas and PTSD influence the health and well-being of individuals with eating disorders throughout the life span.Journal of eating disorders · 2022Review
- Association of Eating Disorders in Prenatal and Perinatal Women and Its Complications in Their Offspring.Cureus · 2022Review
- Feeding Difficulty Among Chinese Toddlers Aged 1-3 Years and Its Association With Health and Development.Frontiers in pediatrics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous studies showed that factors influencing fetal development and neonatal period could lead to lasting alterations in the brain of the offspring, in turn increasing the risk for eating disorders (EDs). This work aims to systematically and critically review the literature on the association of prenatal and perinatal factors with the onset of EDs in the offspring, updating previous findings and focusing on anorexia nervosa (AN) and bulimia nervosa (BN). A systematic literature search was performed on Pubmed, PsycINFO, and Scopus. The drafting of this systematic review was conducted following the PRISMA statement criteria and the methodological quality of each study was assessed by the MMAT 2018. A total of 37 studies were included in this review. The factors that showed a more robust association with AN were higher maternal age, preeclampsia and eclampsia, multiparity, hypoxic complications, prematurity, or being born preterm (< 32 weeks) and small for gestational age or lower birth size. BN was only associated with maternal stress during pregnancy. Many methodological flaws emerged in the considered studies, so further research is needed to clarify these inconsistencies. Altogether, data are suggestive of an association between prenatal and perinatal factors and the onset of EDs in the offspring. Nevertheless, given the methodological quality of the available literature, firm conclusions cannot be drawn and whether this vulnerability is specific to EDs or mental disorders remains to be defined. Also, a strong need for longitudinal and well-designed studies on this topic emerged.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.