Evidence map›Paper›PMID 32766958›Full record

ArticlePurinergic signalling2020

P2X3 receptors contribute to transition from acute to chronic muscle pain.

Carolina Ocanha Jorge, Graciana de Azambuja, Beatriz Botasso Gomes, Hayla Lourenço Rodrigues, Augusto Ducati Luchessi, Maria Cláudia Gonçalves de Oliveira-Fusaro

Open access · greenAbstract read
In one paragraph

Article in Purinergic signalling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Neuroplasticity in the transition from acute to chronic pain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Carolina Ocanha JorgeLaboratory of Pain and Inflammation Research, School of Applied Sciences, State University of Campinas (UNICAMP), Pedro Zaccaria 1300, Limeira, Sao Paulo, Brazil.
Graciana de AzambujaLaboratory of Pain and Inflammation Research, School of Applied Sciences, State University of Campinas (UNICAMP), Pedro Zaccaria 1300, Limeira, Sao Paulo, Brazil.
Beatriz Botasso GomesLaboratory of Pain and Inflammation Research, School of Applied Sciences, State University of Campinas (UNICAMP), Pedro Zaccaria 1300, Limeira, Sao Paulo, Brazil.
Hayla Lourenço RodriguesLaboratory of Pain and Inflammation Research, School of Applied Sciences, State University of Campinas (UNICAMP), Pedro Zaccaria 1300, Limeira, Sao Paulo, Brazil.
Augusto Ducati LuchessiLaboratory of Biotechnology, School of Applied Sciences, State University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.
Maria Cláudia Gonçalves de Oliveira-FusaroLaboratory of Pain and Inflammation Research, School of Applied Sciences, State University of Campinas (UNICAMP), Pedro Zaccaria 1300, Limeira, Sao Paulo, Brazil. maria.fusaro@fca.unicamp.br.ORCID 0000-0001-7676-2317
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate whether the development and/or maintenance of chronic-latent muscle hyperalgesia is modulated by P2X3 receptors. We also evaluate the expression of P2X3 receptors and PKCε of dorsal root ganglions during these processes. A mouse model of chronic-latent muscle hyperalgesia, induced by carrageenan and evidenced by PGE

Indexed as

Acute PainAnimalsChronic PainDisease ProgressionGanglia, SpinalMaleMiceMuscle, SkeletalMyalgiaPain ThresholdPhenolsPolycyclic CompoundsPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X3A-317491PhenolsPolycyclic CompoundsPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X3HyperalgesiaMuscleP2X3 receptorsPKC epsilon

Identifiers

PMID32766958
PMCPMC7524965
OpenAlexW3048032981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.