Evidence map›Paper›PMID 32766769›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2021

Raltegravir-associated Drug-Reaction With Eosinophilia and Systemic Symptoms Syndrome in a Pediatric Patient Without Characteristic Human Leukocyte Antigen B*57:01 or B*53:01 alleles.

Sanya J Thomas, Jacob T Kilgore, Bradford A Becken, Coleen K Cunningham, Amelia B Thompson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sanya J ThomasDepartment of Pediatrics, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Jacob T KilgoreDepartment of Pediatrics, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Bradford A BeckenDepartment of Pediatrics, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Coleen K CunninghamDepartment of Pediatrics, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Amelia B ThompsonDepartment of Pediatrics, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA.
Duke University · USDuke Institute for Health Innovation · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
Pediatric Scientist Development Program (PSDP) [K12]K12HD000850 · NICHD · YALE UNIVERSITY · PI Sallie R. Permar · 1987 to 2026
$44.1M
NIAID NIH HHS P30 AI064518NICHD NIH HHS K12 HD000850
6 · The paper itself

Abstract

We present the first published case of raltegravir-associated drug-reaction with eosinophilia and systemic symptoms (DRESS) syndrome in a child without characteristic human leukocyte antigen haplotypes HLA-B*57:01 or HLA-B*53:01. A 4-year-old African American female with perinatally acquired human immunodeficiency virus infection was hospitalized for DRESS after starting a raltegravir-based antiretroviral regimen.

Indexed as

Drug Hypersensitivity SyndromeEosinophiliaPharmaceutical PreparationsAllelesChildChild, PreschoolFemaleHLA AntigensHLA-B AntigensHumansRaltegravir PotassiumHLA AntigensHLA-B AntigensPharmaceutical PreparationsRaltegravir Potassiumantiretroviral therapydrug-reaction with eosinophilia and systemic symptoms syndromehuman immunodeficiency virushuman leukocyte antigen-B allelesraltegravir

Identifiers

PMID32766769
PMCPMC8023309
OpenAlexW3048030206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.