ArticleBioscience reports2020
An elevated monocyte-to-high-density lipoprotein-cholesterol ratio is associated with mortality in patients with coronary artery disease who have undergone PCI.
Article in Bioscience reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 33 citations in OpenAlex.
- The Systemic Immune-Inflammation Index and High-Sensitivity C-Reactive Protein to High-Density Lipoprotein Cholesterol Ratio Predict Moderate and Severe Coronary Artery Stenosis in Older Patients with Coronary Heart Disease.Clinical interventions in aging · 2026Article
- Association of monocyte to high-density lipoprotein cholesterol ratio with non-calcified plaques in subclinical coronary atherosclerosis: a cross-sectional study in hypertensive patients.Frontiers in endocrinology · 2026Article
- The inflammatory markers MHR and NLR are independent risk factors for adverse events during hospitalization in older adult patients with myocardial injury caused by acute carbon monoxide poisoning: a retrospective cross-sectional study.Medical gas research · 2025Article
- Associations of the Monocyte to High-Density Lipoprotein Cholesterol Ratio With Stroke Prevalence and All-Cause Mortality: Evidence From a Population-Based Study.Brain and behavior · 2025Article
- Association of triglyceride-glucose index with all-cause and non-cardiovascular mortality in patients with obstructive sleep apnea: an age-stratified analysis.Diabetology & metabolic syndrome · 2025Article
- Construction and evaluation of a 180-day readmission prediction model for chronic heart failure patients based on sCD40L.Medicine · 2025Article
- Establishment and validation of a nomogram for predicting intravenous immunoglobulin resistance and coronary artery lesion involvement in Kawasaki disease: a retrospective study.Clinical rheumatology · 2025Article
- Predictive value of combined MHR and Lp(a) for in-stent restenosis in coronary heart disease patients: a study based on GEE model.Frontiers in cardiovascular medicine · 2025Article
- Predictive Significance of the Monocyte-to-High-Density Lipoprotein Cholesterol Ratio in Post-Percutaneous Coronary Intervention Contrast-Induced Nephropathy Among Patients with Coronary Artery Disease.Journal of inflammation research · 2025Article
- hs-CRP/HDL-C can predict the risk of all cause mortality in cardiovascular-kidney-metabolic syndrome stage 1-4 patients.Frontiers in endocrinology · 2025Article
- Monocyte-to-high-density lipoprotein cholesterol ratio and the risk of erectile dysfunction: a study from NHANES 2001-2004.Sexual medicine · 2024Article
- Monocyte to high-density lipoprotein cholesterol ratio predicts poor outcomes in ischaemic heart failure patients combined with diabetes: a retrospective study.European journal of medical research · 2023Observational
- Assessment of Inflammatory Hematological Ratios (NLR, PLR, MLR, LMR and Monocyte/HDL-Cholesterol Ratio) in Acute Myocardial Infarction and Particularities in Young Patients.International journal of molecular sciences · 2023Review
- Predictive value of monocyte to high-density lipoprotein cholesterol ratio and tumor markers in colorectal cancer and their relationship with clinicopathological characteristics.World journal of surgical oncology · 2023Article
- The Impact of Monocyte to High-Density Lipoprotein Cholesterol Ratio on All-Cause and Cardiovascular Mortality in Patients with Transcatheter Aortic Valve Replacement.Journal of personalized medicine · 2023Article
- Assessment of the Prognostic Value of Monocyte-to-HDL Ratio in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.Galen medical journal · 2023Article
- The predictive effect of direct-indirect bilirubin ratio on clinical events in acute coronary syndrome: results from an observational cohort study in north China.BMC cardiovascular disorders · 2022Observational
- Monocyte-to-high-density lipoprotein-cholesterol ratio (MHR) and the risk of all-cause and cardiovascular mortality: a nationwide cohort study in the United States.Lipids in health and disease · 2022Article
- High ratio of monocytes to high-density lipoprotein is associated with hemorrhagic transformation in acute ischemic stroke patients on intravenous thrombolysis.Frontiers in aging neuroscience · 2022Article
- Monocyte/High-Density Lipoprotein Cholesterol Ratio Predicts Vitamin D Deficiency in Male Patients with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the present study was to investigate the association between the monocyte-to-high-density lipoprotein-cholesterol ratio (MHR) and the outcomes of patients with coronary artery disease (CAD) who were treated with percutaneous coronary intervention (PCI).
methodsA total of 5679 CAD patients from CORFCHD-PCI, a retrospective cohort study (identifier: ChiCTR-ORC-16010153), who underwent PCI were included in the study and divided into three tertiles according to their MHR values. The primary outcome was long-term mortality after PCI. The main secondary endpoints were stroke, readmission, and major adverse cardiovascular events (MACEs), defined as the combination of cardiac death, recurrent myocardial infarction, and target vessel reconstruction. The average follow-up time was 35.9 ± 22.6 months.
resultsPatients were divided into three groups according to MHR tertiles: the first tertile (MHR < 0.4; n=1290), second tertile (MHR ≥ 0.4-0.61; n=1878) and third tertile (MHR > 0.61; n=1870). The all-cause mortality (ACM) incidence was significantly lower in the first and second tertiles than in the third tertile (adjusted HR = 0.658, [95% CI: 0.408-0.903], P=0.009 and HR = 0.712, [95% CI: 0.538-0.941], P=0.017, respectively). Cardiac mortality (CM) occurred in 235 patients: 60 (3.1%) in the first tertile group, 74 (3.9%) in the second tertile group and 101 (5.4%) in the third tertile group. There was a significant difference in the CM incidence between the first tertile group and the third tertile group (HR = 0.581, [95% CI: 0.406-0.832], P=0.003), and there was also a difference in the CM incidence between the second tertile group and the third tertile group (HR = 0.690, [95% CI: 0.506-0.940], P=0.019).
conclusionThe present study indicated that an increased MHR was independently associated with long-term mortality in CAD patients who have undergone PCI.
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