Evidence map›Paper›PMID 32766582›Full record

ArticlebioRxiv : the preprint server for biology2020

A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors.

Kai S Yang, Xinyu R Ma, Yuying Ma, Yugendar R Alugubelli, Danielle A Scott, Erol C Vatansever, Aleksandra K Drelich, Banumathi Sankaran, Zhi Z Geng, Lauren R Blankenship and 12 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 10 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 1 country.

Kai S Yang
Xinyu R Ma
Yuying Ma
Yugendar R Alugubelli
Danielle A Scott
Erol C Vatansever
Aleksandra K Drelich
Banumathi Sankaran
Zhi Z Geng
Lauren R Blankenship
Hannah E Ward
Yan J Sheng
Jason C Hsu
Kaci C Kratch
Baoyu Zhao
Hamed S Hayatshahi
Jin Liu
Pingwei Li
Carol A Fierke
Chien-Te K Tseng
Shiqing Xu
Texas A&M University · USThe University of Texas Medical Branch at Galveston · USUniversity of North Texas · USLawrence Berkeley National Laboratory · US

Funding

Develop General Methods for the Synthesis of Proteins with Posttranslational Lysine ModificationsR01GM127575 · NIGMS · TEXAS A&M UNIVERSITY · PI LIU, WENSHE RAY · 2019 to 2022
$1.4M
Studying Reversible Histone Acylations in Nucleosome ContextsR01GM121584 · NIGMS · TEXAS A&M UNIVERSITY · PI LIU, WENSHE RAY · 2017 to 2020
$1.3M
6 · The paper itself

Abstract

The COVID-19 pathogen, SARS-CoV-2, requires its main protease (SC2M

Identifiers

PMID32766582
PMCPMC7402039
OpenAlexW3046110367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.