ArticleCritical care explorations2020
Evaluation of Coronavirus Disease 2019 Severity Using Urine Biomarkers.
Article in Critical care explorations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04681040 (Monitoring of COVID-19 Using Urine POC Kit), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Monitoring of COVID-19 Using Urine POC Kit
Who cites it
19 citing papers in PubMed.
- Acute interstitial nephritis due to acute pyelonephritis in a young woman: diagnostic utility of CK7 and CD10 immunostaining.CEN case reports · 2026Article
- Article
- Urine oxygenation predicts COVID-19 risk.Clinical and experimental nephrology · 2024Review
- Blood perfusion with polymyxin B immobilized columns in patients with COVID-19 requiring oxygen therapy.Scientific reports · 2024Article
- Clustering based on renal and inflammatory admission parameters in critically ill patients admitted to the ICU.PloS one · 2024Article
- Evaluation of Plasma Biomarkers to Predict Major Adverse Kidney Events in Hospitalized Patients With COVID-19.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023Article
- Urinary L-Type Fatty Acid-Binding Protein Predicts Oxygen Demand of COVID-19 in Initially Mild Cases.Critical care explorations · 2023Article
- The Impact and Treatment of COVID-19 in Hemodialysis Patients.Journal of clinical medicine · 2023Article
- The role of kidney injury biomarkers in COVID-19.Renal failure · 2022Review
- Dynamic modulations of urinary sphingolipid and glycerophospholipid levels in COVID-19 and correlations with COVID-19-associated kidney injuries.Journal of biomedical science · 2022Article
- For safe and adequate blood purification therapy in severe COVID-19 ‒ what we have learned so far.Global health & medicine · 2022Review
- Urine sediment findings were milder in patients with COVID-19-associated renal injuries than in those with non-COVID-19-associated renal injuries.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Metformin use in patients hospitalized with COVID-19: lower inflammation, oxidative stress, and thrombotic risk markers and better clinical outcomes.Journal of thrombosis and thrombolysis · 2022Article
- Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19.Cell reports · 2022Article
- Evaluation of Tubular Dysfunction Using Urine Biomarkers in Children with COVID-19.Turkish archives of pediatrics · 2022Article
- Discovery Proteomics for COVID-19: Where We Are Now.Journal of proteome research · 2021Review
- First Experience Addressing the Prognostic Utility of Novel Urinary Biomarkers in Patients With COVID-19.Open forum infectious diseases · 2021Article
- External validation and update of prediction models for unfavorable outcomes in hospitalized patients with COVID-19 in Japan.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2021Article
- Direct hemoperfusion using a polymyxin B-immobilized polystyrene column for COVID-19.Journal of clinical apheresis · 2021Observational
Corrections and comments
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Authors and funding
33 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
subjectsEarly detection of coronavirus disease 2019 in patients likely to develop severe manifestations enables appropriate interventions, including rapid ICU admission. This study was conducted to determine whether noninvasive urine biomarkers can predict the clinical severity of coronavirus disease 2019.
interventionsNot applicable. MEASUREMENTS AND MAIN
resultsThis is single-center study, national center hospital designated for infectious disease. Fifty-eight patients who tested positive for severe acute respiratory syndrome coronavirus 2 in respiratory specimens through real-time reverse transcription-polymerase chain reaction were retrospectively studied. Urinary β2-microglobulin, liver-type fatty acid-binding protein were serially measured. Serum interferon-γ and monocyte chemotactic protein-1 were also evaluated. The 58 patients were assigned into three groups. Patients requiring intensive care were assigned to the severe group (
conclusionsEvaluating urinary biomarkers such as β2-microglobulin and liver-type fatty acid-binding protein may allow determination of coronavirus disease 2019 patients with active cytokines and recognition of patients likely to become critically ill and requiring careful observation and early intervention.
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Registered trials
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