ReviewEuropean endodontic journal2020
Endodontic Periapical Lesion: An Overview on the Etiology, Diagnosis and Current Treatment Modalities.
Review in European endodontic journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
178 citing papers in PubMed, 5 syntheses or guidelines pooled it, 311 citations in OpenAlex.
- Accuracy of Ultrasound Imaging in the Differential Diagnosis of Inflammatory Radicular Cyst and Periapical Granuloma: A Systematic Review and Meta-Analysis of Operative Characteristics.European endodontic journal · 2025Pooled it
- Diagnostic accuracy of periapical radiography and panoramic radiography in the detection of apical periodontitis: a systematic review and meta-analysis.La Radiologia medica · 2024Pooled it
- Disinfection of dental root canals by cold atmospheric plasma: a systematic review and meta-analysis of dental biofilm.Frontiers in oral health · 2024Pooled it
- The role of systemic statins in the inception and healing of apical periodontitis: a systematic review.BMC oral health · 2023Pooled it
- Periapical Healing following Root Canal Treatment Using Different Endodontic Sealers: A Systematic Review.BioMed research international · 2022Pooled it
- Healing Outcome of Different Aqueous-based Calcium Hydroxide Intracanal Medicament in Patients with Pulpal Necrosis and Symptomatic Apical Periodontitis: A Randomised Controlled Trial.European endodontic journal · 2025Trial
- The Impact of Different Final Irrigation Activation Techniques on Postoperative Pain in Single Rooted Mandibular Premolar Teeth: Randomised Clinical Trial.European endodontic journal · 2025Trial
- In vitro evaluation of the sealing ability of combined use of iRoot BP Plus and iRoot SP for root-end filling.Clinical oral investigations · 2023Trial
- Follow-up of periapical inflammation after root canal retreatment and surgical endodontic treatment using dental-dedicated magnetic resonance imaging: a case report.Oral radiology · 2026Article
- Comparative Histopathological Spectrum of Periapical Lesions in Root Canal-Treated and Non-root Canal-Treated Teeth.Cureus · 2026Article
- Four-Octyl Itaconate Alleviates Enterococcus faecalis-Induced Apical Periodontitis by Inhibiting Macrophage M1 Polarisation.International endodontic journal · 2026Article
- Hypoxia Exacerbates Periapical Periodontitis-Associated Pathological Bone Loss via the Hypoxia-Inducible Factor-2α-Calmodulin-Dependent Protein Kinase IV Axis.Cell proliferation · 2026Article
- Rural-Urban and Demographic Inequalities in Dental Pathology and Diagnostic Patterns in Romanian Emergency Care: A Retrospective Tertiary Clinical Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- Effects of resveratrol-enriched endodontic sealants on pulp stem cell viability and collagen production.Acta odontologica latinoamericana : AOL · 2026Article
- A Comparative Study of Caerin 1.1/1.9 and Calcium Hydroxide in the Treatment of Apical Periodontitis in Rats.International dental journal · 2026Article
- Diagnostic Accuracy of Pulp Sensibility Tests and Radiographic Findings for Endodontic-Periodontal Lesions.Cureus · 2026Article
- [Study of the Sealing and Antibacterial Properties of Bioceramic Root Canal Sealers Modified With Quaternary Ammonium Salt].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Potential Association Between Apical Periodontitis and Cardiovascular Disease: A Narrative Review of Evidence and Clinical Implications.Anatolian journal of cardiology · 2026Review
- Single cone versus carrier-based obturation using a premixed bioceramic sealer in postgraduate master cohort: a 36 months retrospective evaluation.Clinical oral investigations · 2026Article
- Initial attachment, viability, proliferation, and migration of osteoblast-like SaOS-2 cells on two resorbable xenogeneic membranes for guided tissue regeneration: ab in vitro experimental study.Restorative dentistry & endodontics · 2026Article
118 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nonsurgical and surgical endodontic treatments have a high success rate in the treatment and prevention of apical periodontitis when carried out according to standard and accepted clinical principles. Nevertheless, endodontic periapical lesions remain in some cases, and further treatment should be considered when apical periodontitis persists. Although several treatment modalities have been proposed for endodontically treated teeth with persistent apical periodontitis, there is a need for less invasive methods with more predictable outcomes. The advantages and shortcomings of existing approaches for the diagnosis and treatment of endodontic periradicular lesions are discussed in this review.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.