ArticleScience advances2020
From asymmetrical to balanced genomic diversification during rediploidization: Subgenomic evolution in allotetraploid fish.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 93 citations in OpenAlex.
- Haplotype-resolved genome ofZoological research · 2026Article
- amh alleles on XY sex chromosomes regulate male differentiation in amphidiploid Carassius auratus.Science China. Life sciences · 2026Article
- Molecular Regulation of Growth in Aquaculture: From Genes to Sustainable Production.Life (Basel, Switzerland) · 2025Review
- Evolutionary Dynamics of Matrix Metalloproteases with Collagenolytic Activity in Teleosts.Animals : an open access journal from MDPI · 2025Article
- The Influence of Genome Composition and Temperature on the Hatching Success and Development of the Offspring of AllotriploidInternational journal of molecular sciences · 2025Article
- Article
- Deep learning reveals determinants of transcriptional infidelity at nucleotide resolution in the allopolyploid line by goldfish and common carp hybrids.Briefings in bioinformatics · 2025Article
- A chromosome-level genome assembly of the mud carp (Cirrhinus molitorella).Scientific data · 2025Article
- Variation and Interaction of Distinct Subgenomes Contribute to Growth Diversity in Intergeneric Hybrid Fish.Genomics, proteomics & bioinformatics · 2025Article
- A telomere-to-telomere genome assembly of koi carp (Cyprinus carpio) using long reads and Hi-C technology.GigaScience · 2025Article
- Telomere-to-telomere chromosome-scale genome assemblies of black and golden koi carp variants support construction of an ancient karyotype of Cypriniformes.GigaScience · 2025Article
- Article
- An improved transcriptome annotation reveals asymmetric expression and distinct regulation patterns in allotetraploid common carp.Communications biology · 2024Article
- Recent and Recurrent Autopolyploidization Fueled Diversification of Snow Carp on the Tibetan Plateau.Molecular biology and evolution · 2024Article
- DNA Methylation and Subgenome Dominance Reveal the Role of Lipid Metabolism in Jinhu Grouper Heterosis.International journal of molecular sciences · 2024Article
- Pan-evolutionary and regulatory genome architecture delineated by an integrated macro- and microsynteny approach.Nature protocols · 2024Review
- Evolutionary divergence of subgenomes in common carp provides insights into speciation and allopolyploid success.Fundamental research · 2024Article
- Identification and effective regulation ofZoological research · 2024Article
- Article
- The Goldfish Genome and Its Utility for Understanding Gene Regulation and Vertebrate Body Morphology.Methods in molecular biology (Clifton, N.J.) · 2024Article
Corrections and comments
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Authors and funding
39 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A persistent enigma is the rarity of polyploidy in animals, compared to its prevalence in plants. Although animal polyploids are thought to experience deleterious genomic chaos during initial polyploidization and subsequent rediploidization processes, this hypothesis has not been tested. We provide an improved reference-quality de novo genome for allotetraploid goldfish whose origin dates to ~15 million years ago. Comprehensive analyses identify changes in subgenomic evolution from asymmetrical oscillation in goldfish and common carp to diverse stabilization and balanced gene expression during continuous rediploidization. The homoeologs are coexpressed in most pathways, and their expression dominance shifts temporally during embryogenesis. Homoeolog expression correlates negatively with alternation of DNA methylation. The results show that allotetraploid cyprinids have a unique strategy for balancing subgenomic stabilization and diversification. Rediploidization process in these fishes provides intriguing insights into genome evolution and function in allopolyploid vertebrates.
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