Evidence map›Paper›PMID 32766348›Full record

ArticleJournal of arthropod-borne diseases2020

Development of A Loop-Mediated Isothermal Amplification (LAMP) Assay for Detection of Relapsing Fever Borreliae.

Faezeh Houmansadr, Mohammad Soleimani, Saied Reza Naddaf

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of arthropod-borne diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Faezeh HoumansadrDepartment of Cellular and Molecular Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Mohammad SoleimaniDepartment of Microbiology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Saied Reza NaddafDepartment of Parasitology, Pasteur Institute of Iran, Tehran, Iran.
Biotechnology Research Center · IRIslamic Azad University, Science and Research Branch · IRPasteur Institute of Iran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to develop a loop-mediated isothermal amplification (LAMP) assay for the rapid detection of tick-borne relapsing fever in resource-limited areas.

methodsA set of six primers were designed based on the conserved regions of the Glycerophosphodiester phosphodiesterase (

resultsThe LAMP detected as low as 90

conclusionThe high sensitivity and specificity of the test, along with the simplicity of the DNA extraction procedure, make the LAMP a reliable and adaptable tool for the diagnosis of tick-borne relapsing fever in rural endemic areas.

Indexed as

glpQIranLAMPRelapsing fever

Identifiers

PMID32766348
PMCPMC7382693
OpenAlexW3015016815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.