Observational studyBioMed research international2020
Prognostic Value of Thyroid Hormone FT3 in General Patients Admitted to the Intensive Care Unit.
Observational study in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Non-thyroidal illness syndrome and isolated low triiodothyronine as prognostic markers in acute illness: a systematic review and meta-analysis.Endocrine · 2026Pooled it
- Association of thyroid hormones and thyroid-stimulating hormone with mortality in adults admitted to the intensive care unit: A systematic review and meta-analysis.Journal of the Chinese Medical Association : JCMA · 2022Pooled it
- Dysnatremia and Endocrine Alterations in Hospitalized COVID-19 Patients: Markers of Systemic Stress Rather than Independent Predictors of Outcomes.Biomedicines · 2026Article
- Non-thyroidal Illness Syndrome and Clinical Outcomes in Critically Ill ICU Patients: A Prospective Cohort Study.Cureus · 2026Article
- The Prognostic Significance of Low-Triiodothyronine Syndrome in Aneurysmal Subarachnoid Hemorrhage.Biomedicines · 2026Article
- Non-Thyroidal Illness Syndrome and Thyroid Autoimmunity in Hospitalized COVID-19 Patients: A Retrospective Study.Journal of clinical medicine · 2025Article
- Total triiodothyronine level associated with disease severity for patients with emergent status.Scientific reports · 2024Article
- Impact of thyroid hormones on predicting the occurrence of persistent inflammation, immunosuppression, and catabolism syndrome in patients with sepsis.Frontiers in endocrinology · 2024Observational
- Similar hypothyroid and sepsis circulating mRNA expression could be useful as a biomarker in nonthyroidal illness syndrome: a pilot study.Archives of endocrinology and metabolism · 2023Article
- Association between dynamic fluctuations in triiodothyronine levels and prognosis among critically ill patients within comprehensive intensive care units.Frontiers in endocrinology · 2023Observational
- Transient low T3 syndrome in patients with COVID-19: a new window for prediction of disease severity.Frontiers in endocrinology · 2023Article
- Nonthyroidal illness syndrome (NTIS) in severe COVID-19 patients: role of T3 on the Na/K pump gene expression and on hydroelectrolytic equilibrium.Journal of translational medicine · 2021Article
- Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients.Endocrinology and metabolism (Seoul, Korea) · 2021Observational
- Thyroid Dysfunction in COVID-19.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low plasma triiodothyronine (T3) concentration indicates nonthyroidal illness syndrome (NTIS), which might be associated with a poor outcome in patients in the intensive care unit (ICU). This study evaluated the relationship between NTIS and prognostic indicators in patients admitted to the ICU and examined the fT3 cut-off points that could be associated with 28-day mortality. This prospective observational study included patients admitted to the ICU of The Third Hospital of Hebei Medical University from February to November 2018. The baseline variables and the occurrence of low free T3 (FT3) were collected. The patients were divided into the NTIS (FT3 < 3.28) and non-NTIS groups. Among 305 patients, 118 (38.7%) were in the NTIS group. FT3 (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.