Evidence map›Paper›PMID 32766261›Full record

ArticleFrontiers in medicine2020

Lung Involvement in Primary Sjögren's Syndrome-An Under-Diagnosed Entity.

Georgios Sogkas, Stefanie Hirsch, Karen Maria Olsson, Jan B Hinrichs, Thea Thiele, Tabea Seeliger, Thomas Skripuletz, Reinhold Ernst Schmidt, Torsten Witte, Alexandra Jablonka and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Manifestations and management of Sjögren's disease.Arthritis research & therapy · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Georgios SogkasDepartment of Immunology and Rheumatology, Medical School Hannover, Hanover, Germany.
Stefanie HirschDepartment of Immunology and Rheumatology, Medical School Hannover, Hanover, Germany.
Karen Maria OlssonDepartment of Respiratory Medicine, Hannover Medical School, Hanover, Germany.
Jan B HinrichsDepartment of Diagnostic and Interventional Radiology, Hannover Medical School, Hanover, Germany.
Thea ThieleDepartment of Immunology and Rheumatology, Medical School Hannover, Hanover, Germany.
Tabea SeeligerDepartment of Neurology, Hannover Medical School, Hanover, Germany.
Thomas SkripuletzDepartment of Neurology, Hannover Medical School, Hanover, Germany.
Reinhold Ernst SchmidtDepartment of Immunology and Rheumatology, Medical School Hannover, Hanover, Germany.
Torsten WitteDepartment of Immunology and Rheumatology, Medical School Hannover, Hanover, Germany.
Alexandra JablonkaDepartment of Immunology and Rheumatology, Medical School Hannover, Hanover, Germany.
Diana ErnstDepartment of Immunology and Rheumatology, Medical School Hannover, Hanover, Germany.
Medizinische Hochschule Hannover · DEGerman Center for Lung Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial lung disease (ILD) represents a frequent extra-glandular manifestation of primary Sjögren's Syndrome (pSS). Limited published data regarding phenotyping and treatment exists. Advances in managing specific ILD phenotypes have not been comprehensively explored in patients with coexisting pSS. This retrospective study aimed to phenotype lung diseases occurring in a well-described pSS-ILD cohort and describe treatment course and outcomes. Between April 2018 and February 2020, all pSS patients attending our Outpatient clinic were screened for possible lung involvement. Clinical, laboratory and high-resolution computed tomography (HRCT) findings were analyzed. Patients were classified according to HRCT findings into five groups: usual interstitial pneumonia (UIP), non-specific interstitial pneumonia (NSIP), desquamative interstitial pneumonia (DIP), combined pulmonary fibrosis and emphysema (CPFE), and non-specific-ILD. Lung involvement was confirmed in 31/268 pSS patients (13%). One-third (10/31) of pSS-ILD patients were Ro/SSA antibody negative. ILD at pSS diagnosis was present in 19/31 (61%) patients. The commonest phenotype was UIP

Indexed as

ESSDAI—EULAR Sjögren's Syndrome Disease Activity Indexinterstitial lung disease (ILD)lung fibrosissicca syndromeSjögren's Syndrome (SS)

Identifiers

PMID32766261
PMCPMC7378373
OpenAlexW3043616480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.