ArticleFrontiers in bioengineering and biotechnology2020
Single-Sample Node Entropy for Molecular Transition in Pre-deterioration Stage of Cancer.
Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Robust signalling entropy estimation for biological process characterisation.Briefings in bioinformatics · 2025Article
- Revealing the critical state and identifying individualized dynamic network biomarker for type 2 diabetes through advanced analysis methods on individual basis.Scientific reports · 2025Article
- Disease prediction by network information gain on a single sample basis.Fundamental research · 2025Article
- Gene expression ranking change based single sample pre-disease state detection.Frontiers in genetics · 2024Article
- The single-sample network module biomarkers (sNMB) method reveals the pre-deterioration stage of disease progression.Journal of molecular cell biology · 2022Article
- Single-cell RNA sequencing reveals the role of immune-related autophagy in spinal cord injury in rats.Frontiers in immunology · 2022Article
- scGET: Predicting Cell Fate Transition During Early Embryonic Development by Single-cell Graph Entropy.Genomics, proteomics & bioinformatics · 2021Article
- Evaluation of Single Sample Network Inference Methods for Metabolomics-Based Systems Medicine.Journal of proteome research · 2021Article
- Dynamic Network Biomarker of Pre-Exhausted CD8Frontiers in immunology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A complex disease, especially cancer, always has pre-deterioration stage during its progression, which is difficult to identify but crucial to drug research and clinical intervention. However, using a few samples to find mechanisms that propel cancer crossing the pre-deterioration stage is still a complex problem. In this study, we successfully developed a novel single-sample model based on node entropy with
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.