Evidence map›Paper›PMID 32765996›Full record

ArticleCureus2020

Comparison of Rates and Outcomes of Readmission to Index vs Non-index Hospitals After Intravenous Thrombolysis in Acute Stroke Patients.

Kristina Shkirkova, Michelle Connor, Drew M Hodis, Krista Lamorie-Foote, Arati Patel, Qinghai Liu, Li Ding, Arun Amar, Nerses Sanossian, Frank Attenello and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kristina ShkirkovaNeurological Surgery, University of Southern California, Keck School of Medicine, Los Angeles, USA.
Michelle ConnorNeurological Surgery, University of Southern California, Los Angeles, USA.
Drew M HodisZilkha Neurogenetic Institute, University of Southern California, Los Angeles, USA.
Krista Lamorie-FooteNeurological Surgery, University of Southern California, Los Angeles, USA.
Arati PatelNeurological Surgery, University of California, San Francisco, San Francisco, USA.
Qinghai LiuNeurological Surgery, University of Southern California, Los Angeles, USA.
Li DingPreventive Medicine, University of Southern California, Los Angeles, USA.
Arun AmarNeurological Surgery, University of Southern California, Los Angeles, USA.
Nerses SanossianNeurology, University of Southern California, Los Angeles, USA.
Frank AttenelloNeurological Surgery, University of Southern California, Keck School of Medicine, Los Angeles, USA.
William MackNeurological Surgery, University of Southern California, Los Angeles, USA.
University of Southern California · USNeurological Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

National and regional systems of stroke care are designed to provide patients with widespread access to hospitals with thrombolytic capabilities. However, such triaging systems may contribute to fragmentation of care. This study aims to compare rates of readmission and outcomes between index and non-index hospitals for stroke patients following intravenous thrombolytic therapy (IVT). This study utilized a nationally representative sample of stroke patients with IVT from the Nationwide Readmissions Database from 2010 to 2014. Descriptive and regression analyses were performed for patient and hospital level factors that influenced 90-day readmissions and regression models were used to identify differences in mortality, complications, and repeat readmissions between patients readmitted to index (facility where IVT was administered) and non-index hospitals. In the study, 49415 stroke patients were treated with IVT, of whom 21.7% were readmitted within 90 days. Among readmissions, 79.4% of patients were readmitted to index hospitals and 20.6% to non-index hospitals. On multivariate logistic regression analysis, index hospital readmission was independently associated with lower frequency of second readmissions (non-index OR 1.09, 95%CI 1.07-1.11, p<0.0001) but not with increased mortality or major complications (p=ns). Approximately one-fifth of stroke patients treated with thrombolysis were readmitted within 90 days, one-fifth of whom were readmitted to non-index hospitals. Although readmission to index hospital was associated with lower frequency of subsequent readmissions, readmission to non-index hospital was not associated with increased mortality or major complications. This difference may be due to standardized algorithms, mature systems of care, and demanding metrics required of stroke centers.

Indexed as

readmissionstrokestroke systems of carethrombolysis

Identifiers

PMID32765996
PMCPMC7398710
OpenAlexW3038810795

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.