Evidence map›Paper›PMID 32765950›Full record

ReviewAging and disease2020

DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) -

Kai Kaarniranta, Elzbieta Pawlowska, Joanna Szczepanska, Janusz Blasiak

Open access · goldAbstract readReview
In one paragraph

Review in Aging and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Role of P2X7R in Retinal Diseases: A Review.Immunity, inflammation and disease · 2025
    Review
  5. Review
  6. Article
  7. The Role of Glutathione in Age-Related Macular Degeneration (AMD).International journal of molecular sciences · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Kai Kaarniranta1Department of Ophthalmology, University of Eastern Finland, Kuopio 70211, Finland and Department of Ophthalmology, Kuopio University Hospital, Kuopio 70029, Finland.
Elzbieta Pawlowska2Department of Orthodontics, Medical University of Lodz, 92-216 Lodz, Poland.
Joanna Szczepanska3Department of Pediatric Dentistry, Medical University of Lodz, 92-216 Lodz, Poland.
Janusz Blasiak4Department of Molecular Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 90-236 Lodz, Poland.
Medical University of Lodz · PLUniversity of Eastern Finland · FIUniversity of Łódź · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DICER1 deficiency in the retinal pigment epithelium (RPE) was associated with the accumulation of

Indexed as

age-related macular degenerationAlu repeatsDICER1miRNA regulationNLRP3 inflammasome

Identifiers

PMID32765950
PMCPMC7390522
OpenAlexW3046454798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.