Evidence map›Paper›PMID 32765895›Full record

ArticleNeuro-oncology practice2020

Community economic factors influence outcomes for patients with primary malignant glioma.

Aaron Bower, Fang-Chi Hsu, Kathryn E Weaver, Caleb Yelton, Rebecca Merrill, Robert Wicks, Mike Soike, Angelica Hutchinson, Emory McTyre, Adrian Laxton and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Neuro-oncology practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Environmental Hazards and Glial Brain Tumors: Association or Causation?International journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Aaron BowerWake Forest School of Medicine, Winston-Salem, North Carolina.
Fang-Chi HsuDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Kathryn E WeaverDepartments of Social Sciences and Health Policy and Implementation Science, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Caleb YeltonWake Forest Baptist Medical Center Department of Neurology, Winston-Salem, North Carolina.
Rebecca MerrillWake Forest School of Medicine, Winston-Salem, North Carolina.
Robert WicksWake Forest Baptist Medical Center Department of Neurosurgery, Winston-Salem, North Carolina.
Mike SoikeWake Forest Baptist Medical Center Department of Radiation Oncology, Winston-Salem, North Carolina.
Angelica HutchinsonWake Forest Baptist Medical Center Department of Social Sciences and Health Policy, Winston-Salem, North Carolina.
Emory McTyreWake Forest Baptist Medical Center Department of Radiation Oncology, Winston-Salem, North Carolina.
Adrian LaxtonWake Forest Baptist Medical Center Department of Neurosurgery, Winston-Salem, North Carolina.
Stephen TatterWake Forest Baptist Medical Center Department of Neurosurgery, Winston-Salem, North Carolina.
Christina CramerWake Forest Baptist Medical Center Department of Radiation Oncology, Winston-Salem, North Carolina.
Michael ChanWake Forest Baptist Medical Center Department of Radiation Oncology, Winston-Salem, North Carolina.
Glenn LesserWake Forest Baptist Medical Center Department of Neurology, Winston-Salem, North Carolina.
Roy E StrowdWake Forest School of Medicine, Winston-Salem, North Carolina.
Atrium Health Wake Forest Baptist · USWake Forest University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Wake Forest Clinical and Translational Science AwardKL2TR001421 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MILLER, DAVID P · 2015 to 2023
$5.8M
NCATS NIH HHS KL2 TR001421NCI NIH HHS P30 CA012197
6 · The paper itself

Abstract

backgroundCommunity economics and other social health determinants influence outcomes in oncologic patient populations. We sought to explore their impact on presentation, treatment, and survival in glioma patients.

methodsA retrospective cohort of patients with glioma (World Health Organization grades III-IV) diagnosed between 1999 and 2017 was assembled with data abstracted from medical record review. Patient factors included race, primary care provider (PCP) identified, marital status, insurance status, and employment status. Median household income based on zip code was used to classify patients as residing in high-income communities (HICs; ie, above the median state income) or low-income communities (LICs; ie, below the median state income). The Kaplan-Meier method was used to assess overall survival (OS); Cox proportional hazards regression was used to explore associations with OS.

resultsIncluded were 312 patients, 73% from LICs. Survivors residing in LICs and HICs did not differ by age, sex, race, tumor grade, having a PCP, employment status, insurance, time to presentation, or baseline performance status. Median OS was 4.1 months shorter for LIC patients (19.7 vs 15.6 mo; hazard ratio [HR], 0.75; 95% CI: 0.56-0.98,

conclusionsThe economic status of a glioma patient's community may influence survival. Future efforts should investigate potential mechanisms such as health care access, stress, treatment adherence, and social support.

Indexed as

glioblastomasocioeconomicssurvival

Identifiers

PMID32765895
PMCPMC7393281
OpenAlexW3013788339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.