ArticleExperimental and therapeutic medicine2020
Variation of total serum sialic acid concentration in postmenopausal women.
Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Estradiol regulates osteoclast sialylation via ST3Gal1 in postmenopausal osteoporosis.Bone research · 2026Article
- Simultaneous ManNAc and Neu5Ac Quantification in Human Sera by LC-MS/MS.International journal of molecular sciences · 2026Article
- Total Sialic Acid, Antioxidant Enzyme Activities, Trace Elements, and Vitamin Status Before and After Surgery in Women with Uterine Myoma and Endometrial Cancer.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- Article
- Impact of estrogen on IgG glycosylation and serum protein glycosylation in a murine model of healthy postmenopause.Frontiers in endocrinology · 2023Article
- CD33 rs2455069 SNP: Correlation with Alzheimer's Disease and Hypothesis of Functional Role.International journal of molecular sciences · 2022Article
- Evaluation of serum total sialic acid in moderate COVID-19 patients with and without gastrointestinal tract manifestations.Tissue & cell · 2022Article
- Correlations of sialic acid with glycated hemoglobin A1c and glycemia in postmenopausal women with type-2 diabetes mellitus.Experimental and therapeutic medicine · 2021Article
- 2nd Special Issue: Tackling key immunological and immuno-dermatological pathways and their link to treatment options.Experimental and therapeutic medicine · 2020Article
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Authors and funding
3 authors.
Funding
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Abstract
Given its location and ubiquitous distribution, sialic acid can mediate or modulate a wide variety of physiological and pathological processes; however, there is scarce data regarding the associations between sialic acid serum levels and sex, age and menopause. The present study evaluated the age-related changes in serum sialic acid (SA) levels in 97 elderly subjects, including men and postmenopausal women. A significant increase in serum levels of sialic acid in postmenopausal women and a significant decrease in men were observed in an age-dependent manner. Furthermore, in postmenopausal women, positive correlations were observed between the total serum sialic acid level and age in all decades and subgroups. The total serum concentration of sialic acid in the postmenopausal women group exhibited a particular pattern; significantly lower levels were observed in subjects in the intermediate postmenopausal period compared with those in the first decade of post menopause and then higher levels again as the women get older (late climax), thus the concentration increased according to the age of the individual.
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