Evidence map›Paper›PMID 32765730›Full record

ArticleExperimental and therapeutic medicine2020

Cytomegalovirus seroprevalence in pregnant women in the western region of Romania: A large-scale study.

Florin Gorun, Sorin Motoi, Daniel Malita, Dan Bogdan Navolan, Dragos Nemescu, Tudor Rares Olariu, Marius Craina, Tatjana Vilibic-Cavlek, Ioana Ciohat, Daniel Boda and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  13. The Impact of LatentMicroorganisms · 2022
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  18. Impact of Stress and Financials on Romanian Infertile Women Accessing Assisted Reproductive Treatment.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Florin GorunDepartment of Obstetrics and Gynecology, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Sorin MotoiDepartment of Medical Imaging and Radiology, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Daniel MalitaDepartment of Medical Imaging and Radiology, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Dan Bogdan NavolanDepartment of Obstetrics and Gynecology, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Dragos NemescuDepartment of Obstetrics and Gynecology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Tudor Rares OlariuDepartment of Parasitology, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Marius CrainaDepartment of Obstetrics and Gynecology, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Tatjana Vilibic-CavlekDepartment of Virology, Croatian Institute of Public Health, 10000 Zagreb, Croatia, Antenatal Laboratory, Emergency Clinical City Hospital, 300202 Timisoara, Romania.
Ioana CiohatAntenatal Laboratory, Emergency Clinical City Hospital, 300202 Timisoara, Romania.
Daniel BodaDermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Amadeus DobrescuDepartament of Surgery, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROCarol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · ROGrigore T. Popa University of Medicine and Pharmacy · ROHrvatski zavod za javno zdravstvo · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) infection is the most common congenital infection worldwide, and remains a significant cause of the neurological deficiency and sensory deafness in developed countries. Maternal primary infection, reactivation or reinfection during pregnancy may lead to fetal infection and congenital CMV syndrome. The purpose of this study was to analyze the CMV seroprevalence according to demographic features of pregnant women in western Romania as well as the evolution of CMV immunity in two time intervals. IgG anti-CMV antibodies were tested in sera of 8,951 pregnant women during two successive intervals: 2008-2010 (n=1466) and 2015-2018 (n=7485). The CMV seroprevalence in women of reproductive age decreased from 94.6 to 91.80% in the last decade. The seroprevalence was higher in women from rural areas compared with those from urban areas. These results show that the western region of Romania has a low-risk profile for primary CMV infection during pregnancy due to a large number of seropositive women. However, this risk has increased in the last ten years, from 5.4 to 8.2%, which may show the need to implement a national screening program.

Indexed as

congenital CMV syndromecytomegalovirusdemographypregnant womenseroprevalence

Identifiers

PMID32765730
PMCPMC7401893
OpenAlexW3037107335

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.