Evidence map›Paper›PMID 32765723›Full record

ReviewExperimental and therapeutic medicine2020

New oral anticoagulants - possible extension to other indications (Review).

Crista Loredana Laslo, Nicolae Bacalbasa, Ana Maria Alexandra Stanescu, Mara Carsote, Simona Bungau, Marius Rus, Ovidiu Gabriel Bratu, Camelia Cristina Diaconu

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Portal vein thrombosis: A concise review (Review).Experimental and therapeutic medicine · 2021
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Crista Loredana LasloInternal Medicine Department, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania.
Nicolae Bacalbasa'Carol Davila' University of Medicine and Pharmacy, Department 13 Obstetrics-Gynecology, 'Ion Cantacuzino' Clinical Hospital, 030167 Bucharest, Romania.
Ana Maria Alexandra Stanescu'Carol Davila' University of Medicine and Pharmacy, Family Medicine Department, 050474 Bucharest, Romania.
Mara Carsote'Carol Davila' University of Medicine and Pharmacy, Department 2 Endocrinology, National Institute of Endocrinology 'C.I. Parhon', 011863 Bucharest, Romania.
Simona BungauUniversity of Oradea, Faculty of Medicine and Pharmacy, Department of Pharmacy, 410028 Oradea, Romania.
Marius RusUniversity of Oradea, Faculty of Medicine and Pharmacy, Department of Medical Disciplines, 410087 Oradea, Romania.
Ovidiu Gabriel Bratu'Carol Davila' University of Medicine and Pharmacy, Urology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania.
Camelia Cristina Diaconu'Carol Davila' University of Medicine and Pharmacy, Internal Medicine Department, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROUniversity of Oradea · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anticoagulant treatment is necessary in various conditions, with curative or preventive purposes. Until recently, the only oral anticoagulants available have been vitamin K antagonists. To overcome the disadvantages of the antivitamin K oral anticoagulants, new oral anticoagulants (NOACs) have been developed and included in clinical trials. After more than 60 years of using vitamin K antagonists, the introduction of NOACs represent a medical breakthrough, with promising prospects. Due to their promising results and better safety profile, NOACs have become an appealing alternative to vitamin K antagonists in a short period of time. NOACs have been approved for the prevention and treatment of venous thromboembolism and for the prevention of stroke in patients with nonvalvular atrial fibrillation. Starting with postoperative venous thromboprophylaxis after hip replacement surgery, NOACs have been approved also for other clinical situations. Rivaroxaban is the first oral anticoagulant approved to be used in combination with an antiplatelet agent to prevent atherothrombotic events in adults with coronary artery disease and/or peripheral artery disease. However, further investigation is needed to establish which group of patients would benefit most from this medical approach. Furthermore, preliminary studies have shown that NOACs seem to be a reasonable choice of anticoagulation for patients with cancer, but further studies are expected.

Indexed as

atherosclerotic vascular diseasecoronary artery diseasenew oral anticoagulantsperipheral arterial diseasesvitamin K antagonists

Identifiers

PMID32765723
PMCPMC7401725
OpenAlexW3023730180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.