Evidence map›Paper›PMID 32765718›Full record

ArticleExperimental and therapeutic medicine2020

Severe DRESS syndrome after carbamazepine intake in a case with multiple addictions: A case report.

Daniela Vrinceanu, Mihai Dumitru, Adrian Stefan, Adriana Neagos, Gabriela Musat, Elena Adriana Nica

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Experimental and therapeutic medicine · 2021
    Review
  4. Article
  5. Respiratory allergies: Salicaceae sensitization (Review).Experimental and therapeutic medicine · 2021
    Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Daniela VrinceanuENT Department, Bucharest Emergency University Hospital, 010271 Bucharest, Romania.
Mihai DumitruDepartment of Anatomy, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Adrian StefanENT Department, Bucharest Emergency University Hospital, 010271 Bucharest, Romania.
Adriana NeagosENT Department, Târgu Mureş University of Medicine and Pharmacy, 540139 Târgu Mureş, Romania.
Gabriela MusatENT Department, 'Sânta Maria' Clinical Hospital, 011172 Bucharest, Romania.
Elena Adriana NicaDepartment of Anesthesia and ICU, Bucharest Emergency University Hospital, 020021 Bucharest, Romania.
Bucharest Emergency University HospitalClinical Emergency Hospital Bucharest · ROCarol Davila University of Medicine and Pharmacy · ROUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A case is presented of a male with drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by carbamazepine intake. The patient presented all the elements of DRESS syndrome: Skin reaction, fever, enlargement of the lymph nodes, increased eosinophils and lymphocytes, with associated organ dysfunctions. The patient was admitted with acute laryngeal edema and imminence of respiratory insufficiency. The escalation of symptoms for this syndrome is typical, even after the administering of the the culprit medicine has ceased. However, in this case, the most difficult aspect was the complex treatment scheme prior to admission. All medical compounds involved in the background treatment were substituted with other substances in order to control the immune response. Current knowledge regarding DRESS is reviewed and possible influence of various etiologies over the present case are discussed. Clinicians should be aware of this rare situation with life-threatening potential. We benefited from the advantage of reuniting the knowledge of a complex team of experts from various tertiary emergency units in Romania.

Indexed as

addictioncarbamazepineDRESS syndromeeosinophiliarespiratory distress

Identifiers

PMID32765718
PMCPMC7401925
OpenAlexW3036262739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.