Evidence map›Paper›PMID 32765606›Full record

ArticleJournal of oncology2020

Low Expression of DDX60 Gene Might Associate with the Radiosensitivity for Patients with Breast Cancer.

Dongrun Xin, Jingfang Liu, Jincheng Gu, Yujie Ji, Jiawei Jin, Lu Sun, Qingliang Tai, Jianping Cao, Ye Tian, Hualong Qin and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  7. DNA and RNA Binding Proteins: From Motifs to Roles in Cancer.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Dongrun XinDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Jingfang LiuDepartment of Gynaecology and Obstetrics, The First Affiliated Hospital of Soochow University, Suzhou 215123, China.
Jincheng GuDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Yujie JiDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Jiawei JinDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Lu SunDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Qingliang TaiDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou 215123, China.
Jianping CaoState Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, China.
Ye TianDepartment of Radiotherapy & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou 215123, China.
Hualong QinDepartment of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215123, China.ORCID https://orcid.org/0000-0003-1300-9533
Zaixiang TangDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou 215123, China.ORCID https://orcid.org/0000-0003-4981-3347
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DEXD/H box helicase 60 (DDX60) is a new type of DEAD-box RNA helicase, which is induced to express after virus infection. It might involve in antiviral immunity by promoting RIG-I-like receptor-mediated signal transduction. In addition, previous studies had shown that the expression of DDX60 is related to cancer, but there was still a lack of relevant research in breast cancer. In this study, we used the information of patients with breast cancer in the TCGA database for statistical analysis and found that the breast cancer patients with low expression of DDX60 exhibited radiosensitivity. Comparing the radiotherapy groups with the nonradiotherapy groups, for patients with low expression of DDX60, the adjusted hazard ratio (HR) values for radiotherapy were 0.244 (0.064-0.921) and 0.199 (0.062-0.646) in the training and validation datasets, with the

Identifiers

PMID32765606
PMCPMC7387961
OpenAlexW3043444114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.