Evidence map›Paper›PMID 32765468›Full record

ArticleFrontiers in microbiology2020

Dectin-1 Facilitates IL-18 Production for the Generation of Protective Antibodies Against

Hui Shen, Yuetian Yu, Si-Min Chen, Juan-Juan Sun, Wei Fang, Shi-Yu Guo, Wei-Tong Hou, Xi-Ran Qiu, Yu Zhang, Yuan-Li Chen and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. The pathogenicity and future treatment strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Article
  4. Review
  5. Vaccines · 2023
    Article
  6. Vaccines against candidiasis: Status, challenges and emerging opportunity.Frontiers in cellular and infection microbiology · 2022
    Review
  7. Article
  8. The Impact of NLRP3 Activation on Hematopoietic Stem Cell Transplantation.International journal of molecular sciences · 2021
    Review
  9. Review
  10. Article
  11. Paracoccidioidomycosis Protective Immunity.Journal of fungi (Basel, Switzerland) · 2021
    Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Hui ShenDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yuetian YuDepartment of Rheumatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Si-Min ChenDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Juan-Juan SunDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Wei FangDepartment of Anesthesiology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Shi-Yu GuoDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Wei-Tong HouDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Xi-Ran QiuDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yu ZhangDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yuan-Li ChenDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yi-Da WangDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Xin-Yu HuDepartment of Anesthesiology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Liangjing LuDepartment of Rheumatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yuan-Ying JiangDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zui ZouDepartment of Anesthesiology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Mao-Mao AnDepartment of Pharmacology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Shanghai Tenth People's Hospital · CNTongji University · CNSecond Military Medical University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive candidiasis (IC) is one of the leading causes of death among immunocompromised patients. Because of limited effective therapy treatment options, prevention of IC through vaccine is an appealing strategy. However, how to induce the generation of direct candidacidal antibodies in host remains unclear.

Indexed as

antibodyC. albicansdectin-1invasive candidiasisvaccine

Identifiers

PMID32765468
PMCPMC7378971
OpenAlexW3043814893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.