Evidence map›Paper›PMID 32765115›Full record

ArticleHIV/AIDS (Auckland, N.Z.)2020

Correlates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0-14 Years in Tanzania.

Amon Exavery, John Charles, Erica Kuhlik, Asheri Barankena, Amal Ally, Tumainiel Mbwambo, Christina Kyaruzi, Godfrey Martin Mubyazi, Levina Kikoyo, Elizabeth Jere

Open access · goldAbstract read
In one paragraph

Article in HIV/AIDS (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.0field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Amon ExaveryPact, Dar es Salaam, Tanzania.ORCID 0000-0001-8545-1801
John CharlesPact, Dar es Salaam, Tanzania.
Erica KuhlikPact, Inc., Washington, DC, WA 20036, USA.
Asheri BarankenaPact, Dar es Salaam, Tanzania.
Amal AllyPact, Dar es Salaam, Tanzania.
Tumainiel MbwamboPact, Dar es Salaam, Tanzania.ORCID 0000-0002-8745-2856
Christina KyaruziPact, Dar es Salaam, Tanzania.
Godfrey Martin MubyaziNational Institute for Medical Research (NIMR), Dar es Salaam, Tanzania.
Levina KikoyoPact, Dar es Salaam, Tanzania.
Elizabeth JerePact, Dar es Salaam, Tanzania.
Consumer Healthcare Products Association · USNational Institute for Medical Research · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2018, only 65% of Tanzanian children aged 0-14 years living with human immunodeficiency virus (HIV) were on treatment, suggesting that challenges exist. This study explores factors associated with uptake of antiretroviral therapy (ART) among HIV-positive orphans and vulnerable children (OVC).

methodsData are from the USAID Kizazi Kipya project that aims to increase the uptake of HIV/AIDS and other health and social services by OVC and their caregivers. HIV-positive OVC aged 0-14 years who were enrolled in the project from January 2017 to September 2018 were analyzed. ART status (off ART or on ART) was the outcome variable. Multivariate analysis was performed using multilevel logistic regression.

resultsOf the 10,047 HIV-positive OVC aged 0-14 years analyzed, 93.5% were currently on ART at enrollment. In the multivariate analysis, OVC with male caregivers were 4-times more likely than those with female caregivers to be on ART (OR=4.03, 95% CI=1.49-10.90). OVC with HIV-positive caregivers were 12-times more likely than those with HIV-negative caregivers to be on ART (OR=12.0, 95% CI=3.81-37.70). OVC with caregivers who did not disclose their HIV status were 74% less likely to be on ART than OVC of HIV-negative caregivers (OR=0.26, 95% CI=0.08-0.90). OVC living in urban areas were more than 5-times as likely as their rural counterparts to be on ART (OR=5.55, 95% CI=2.21-14.0).

conclusionThe majority of the OVCLHIV in the current study were currently on ART (93.5%) at enrollment. However, uptake of ART by the OVC was dependent on factors external to themselves. Advancing ART uptake may require targeting OVC of female caregivers, OVC of HIV-negative caregivers, as well as OVC of caregivers of undisclosed HIV statu, and rural areas.

Indexed as

0–14 yearsAIDSantiretroviral therapyHIVorphansTanzaniauptakevulnerable children

Identifiers

PMID32765115
PMCPMC7367717
OpenAlexW3041381535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.